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Institution
Universität Leipzig
Paul-Flechsig-Institut für Hirnforschung
Address
Liebigstraße 19
04103 Leipzig
Deutschland
GERiT
This institution in GERiT
04103 Leipzig
Projects
Research Grants
Current projects
The role of brevican in cochlear function and normal hearing through its interaction with hair cells and bone
(Applicant
Sonntag, Mandy
)
Unraveling the metabolic action of polyamines on muscle homeostasis in health & obesity
(Applicant
Ost, Mario
)
Completed projects
Advancing the Retina Implant: Exploring the separation of ON and OFF responses in normal and degenerated mouse retina stimulated electrically with the subretinal implant Alpha AMS.
(Applicant
Hosseinzadeh, Ph.D., Zohreh
)
Are alpha-synuclein fragments novel substrates of glutaminyl cyclase?
(Applicant
Roßner, Steffen
)
Die Bedeutung von Gliotransmittern für den Verlauf einer reaktiven Gliose
(Applicant
Pannicke, Thomas
)
Drug-Targeting mit Nanopartikeln gegen experimentell induzierte ß-Amyloid-Ablagerungen und abnorm phosphoryliertes Protein Tau im Gehirn von Kaninchen und transgenen Mäusen mit humanem ß-Amyloid-Präkursorprotein
(Applicant
Härtig, Wolfgang
)
Effekt der exzitatorischen synaptischen Aktivität auf die Prozessierung des Amyloidvorläuferproteins APP
(Applicant
Roßner, Steffen
)
Enzymatic regulation of CCL2 bioactivity in neuroinflammation
(Applicants
Roßner, Steffen
;
Schilling, Stephan
)
Identifikation und funktionelle Charakterisierung molekularer Mediatoren der Kaliumkanalexpression in retinalen Gliazellen
(Applicant
Biedermann, Bernd
)
Interaction of interleukin-1 with the cholinergic signal transduction cascade and its importance for cholinergic deficits in Alzheimer´s disease
(Applicant
Schliebs, Reinhard
)
Is the neurotoxicity of amyloid-beta AGE-related?
(Applicant
Schliebs, Reinhard
)
Morphogenetische Bedeutung von p21ras in differenzierten Neuronen: Morphologische Analyse, Modellierung und Computersimulation
(Applicant
Gärtner, Ulrich
)
Pathomorphologie und Pathophysiologie der Borna-Disease-Virus (BDV)-induzierten Netzhautdegeneration
(Applicant
Pannicke, Thomas
)
Regulation des Amyloidvorläuferprotein-Metabolismus und der ß-Amyloidplaque-Bildung durch Proteinkinase C-abhängige Mechanismen in vivo
(Applicant
Roßner, Steffen
)
Selektive Proteinkinase-Inhibitoren als Wirkstoffe gegen Neurodegeneration
(Applicants
Hilgeroth, Andreas
;
Holzer, Max
;
Sippl, Wolfgang
)
Signatures of modified Abeta peptides in brains of Alzheimer’s disease subjects revealed by novel monoclonal antibodies
(Applicants
Roßner, Steffen
;
Schilling, Stephan
)
Site specific phosphorylation of tau protein employs signal transduction causing neurodegeneration
(Applicant
Holzer, Max
)
Research Units
Completed projects
CD14 as a Gate Keeper in Microglial Responses to PAMPs and DAMPs
(Applicant
Brück, Wolfgang
)
Regulation of Wnt signaling in macrophage-induced malignant invasion
(Applicant
Binder, Claudia
)
Collaborative Research Centres
Completed projects
Thrombin als Stimulus und Modulator mikroglialer Aktivierung
(Project Head
Hanisch, Uwe-Karsten
)
CRC/Transregios
Completed projects
Integrated Research Training Group
(Project Heads
Hanisch, Uwe-Karsten
;
Kettenmann, Helmut
)
Phenotypic diversity of microglia
(Project Heads
Brück, Wolfgang
;
Hanisch, Uwe-Karsten
)
Additional Information
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