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Institution
Julius-Maximilians-Universität Würzburg
Biozentrum
Theodor-Boveri-Institut für Biowissenschaften
Lehrstuhl für Mikrobiologie
Address
Am Hubland
97074 Würzburg
Deutschland
GERiT
This institution in GERiT
97074 Würzburg
Projects
Priority Programmes
Completed projects
Evolution von Pathogenität bei fakultativ intrazellulären Bakterien der Gattung Listeria
(Applicant
Kreft, Jürgen
)
Induction of apoptosis by the PorB porin of Neisseria gonorrhoeae: A paradigm for the evolution of programmed cell death
(Applicant
Rudel, Thomas
)
Infection of endothelium with Chlamydophila pneumoniae
(Applicant
Rudel, Thomas
)
Simkania negevensis containing vacuoles: Formation, trafficking and subversion of host signaling
(Applicant
Rudel, Thomas
)
Research Grants
Current projects
An integrated approach using dual 13C-profiling and RNA-sequencing for unravelling the metabolic programs of the intracellular forms of Chlamydia trachomatis and their host cells
(Applicants
Eisenreich, Wolfgang
;
Rudel, Thomas
)
Completed projects
Antisense regulation of Opa expression in Neisseria gonorrhoeae
(Applicant
Rudel, Thomas
)
Charakterisierung der Signaltransduktionsprozesse bei der chemotaktischen Antwort von Helicobacter pylori
(Applicant
Beier, Dagmar
)
Charakterisierung genregulatorischer Prozesse in Helicobacter pylori
(Applicant
Beier, Dagmar
)
EHEC hemolysin: Molecular and cellular mechanisms of host injury
(Applicant
Karch, Helge
)
Functional characterization of the pH-sensing ArsRS two-component system of Helicobacter pylori and of its regulon
(Applicant
Beier, Dagmar
)
Genetic and immunologic basis of pathogenic and mutualistic interactions between bacteria and their ant hosts
(Applicant
Gross, Roy
)
Genomweite Charakterisierung der Zweikomponenten-Systeme von Listeria monocytogenes
(Applicant
Beier, Dagmar
)
Identification of virulence factors mediating phagosomal escape of Staphylococcus aureus by transposon insertion site deep sequencing
(Applicant
Fraunholz, Martin J.
)
Import and assembly of mitochondrial outer membrane proteins - identification of new factors and import signals
(Applicants
Kozjak-Pavlovic, Vera
;
Rudel, Thomas
)
Wahrnehmung von extra- und intrazellulären Signalen durch das unorthodoxe Zwei-Komponenten-System BvgAS von Bordetellen und Kopplung des Virulenzregulons mit Stoffwechsel- und Stressantwortgenen
(Applicant
Gross, Roy
)
Research Units
Completed projects
FOR 2123: Sphingolipid Dynamics in Infection Control
(Spokesperson
Schneider-Schaulies, Sibylle
)
Role of the acid sphingomyelinase/ceramide system in lung edema induced by Staphylococcus aureus toxin
(Applicants
Fraunholz, Martin J.
;
Gulbins, Erich
)
Sphingolipids in gonococcal infection
(Applicant
Rudel, Thomas
)
Sphingolipids in gonococcal infection
(Applicant
Rudel, Thomas
)
Collaborative Research Centres
Current projects
Central Tasks of the Collaborative Research Centre
(Project Head
Rudel, Thomas
)
Mechanisms driving chlamydial persistence and ascending infection in the female reproductive tract
(Project Head
Rudel, Thomas
)
Molecular decision points underlying the systemic spreading of Staphylococcus aureus
(Project Heads
Fraunholz, Martin J.
;
Medina, Ph.D., Eva
)
SFB 1583: Decisions in Infectious Diseases (DECIDE)
(Spokesperson
Rudel, Thomas
)
Systems biology approach to identify key molecular decision points for intracellular persistence during infection
(Project Head
Brochado, Ana Rita
)
Completed projects
Active Agents against Acute and Disseminating Neisseria Infections
(Project Heads
Kozjak-Pavlovic, Vera
;
Rudel, Thomas
)
Charakterisierung der symbiontischen Beziehung von intrazellulären Bakterien und Ameisen
(Project Head
Gross, Roy
)
Evolution von pathogenen Eigenschaften am Beispiel des Genus Bordetella
(Project Head
Gross, Roy
)
Research Fellowships
Completed projects
Determining the function of the plastids in the human pathogen Toxoplasma gondii (Apicomplexa) with biochemical and computational methods
(Applicant
Fraunholz, Martin J.
)
DIP Programme
Completed projects
A search for new cancer drug targets: The E40RF4 Network of cancer cell-specific apoptosis
(Applicants
Kleinberger, Tamar
;
Rudel, Thomas
)
Major Research Instrumentation
Completed projects
Confocal-laser-scanning-microscope
Konfokales Laserscanning-Mikroskop
Zell-Sorter
CRC/Transregios
Completed projects
Host cell death induced by Staphylococcus aureus and its linkage to phagosomal escape
(Project Heads
Fraunholz, Martin J.
;
Rudel, Thomas
;
Sinha, Bhanu
)
Post-invasion events in Staphylococcus aureus-infected host cells - A combined transcriptomics/proteomics in vivo approach
(Project Heads
Rudel, Thomas
;
Sinha, Bhanu
;
Vogel, Jörg
;
Völker, Uwe
)
International Research Training Groups
Completed projects
GRK 587: Regulation of Genes and Pathogens, Host Response during Infectious Diseases, Detection of Substances Influencing Gene Expression and Pathogens
(Spokesperson
Morschhäuser, Joachim
)
Research Training Groups
Current projects
GRK 2157: 3D Tissue Models for Studying Microbial Infections by Human Pathogens
(Spokesperson
Rudel, Thomas
)
GRK 2243: Understanding Ubiquitylation: From Molecular Mechanisms To Disease
(Spokesperson
Buchberger, Alexander
)
Completed projects
GRK 2581: Metabolism, topology and cx)mpartmentalization of membrane proximal lipid and signaling components in infection
(Spokesperson
Seibel, Jürgen
)
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