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Universitätsklinikum Münster
Zentrum für Molekularbiologie der Entzündung (ZMBE)
Institut für Experimentelle Pathologie

Address Von-Esmarch-Straße 56
48149 Münster
Deutschland

GERiT This institution in GERiT

48149 Münster

Projects

Research Grants
- Completed projects
  - Der neutrophile Granulozyt und sein Sekret: Initiator und Modulator der Atherosklerose?
    (Applicant Söhnlein, Oliver )
  - Genome-Wide analysis of Marsupial Retroposons: Phylogenetic markers for reconstructing their Evolution
    (Applicant Nilsson Janke, Ph.D., Maria )
  - Influenza A virus induced cellular and viral microRNAs in viral replication and host defence
    (Applicants Brosius, Jürgen ; Ludwig, Stephan )
  - LINE-Retrotranspositions-Phylogenie der Vögel (Aves)
    (Applicant Schmitz, Jürgen )
  - Molekulare Evolution und SINE Transpositionen in Rodentia
    (Applicant Schmitz, Jürgen )
  - Neutrophils fatten atherosclerotic lesions
    (Applicant Söhnlein, Oliver )
  - Neutrophils in atherosclerotic plaque destabilization
    (Applicant Söhnlein, Oliver )
  - Resolution of inflammation in atherosclerosis
    (Applicant Söhnlein, Oliver )
  - Role of endocannabinoid system and circadian rhythm in post-myocardial infarction healing
    (Applicant Steffens, Sabine )
  - The power of ancient retroposed sequences to resolve problematic mammalian evolutionary questions
    (Applicant Schmitz, Jürgen )
Research Units
- Completed projects
  - Charakterisierung des RNA-Transportes in Neuronen am Beispiel der nicht-kodierenden BC200 RNA
    (Applicant Kremerskothen, Joachim )
  - Intrazellulärer RNA-Transport
    (Applicant Richter, Dietmar )
  - Rolle von Alarminen aus neutrophilen Granulozyten in der Atherosklerose
    (Applicant Söhnlein, Oliver )
Research data and software
- Completed projects
  - Retrogenomic software and databases to solve evolutionary questions
    (Applicant Schmitz, Jürgen )
Research Fellowships
- Completed projects
  - Funktionelle Interaktion zwischen Sekretionsprodukten neutrophiler Granulozyten und Monozyten in Entzündungen
    (Applicant Söhnlein, Oliver )
Clinical Research Units
- Current projects
  - KFO 342: Organ Dysfuncion During Systemic Inflammation
    (Spokesperson Zarbock, Alexander )
  - Targeting nociceptors to modulate neutrophil mobilization and homing in sepsis
    (Applicants Söhnlein, Oliver ; Wagner, Nana-Maria )
Collaborative Research Centres
- Current projects
  - Hyperglycemia-induced metabolic reprogramming drives neutrophil cytotoxicity in atherosclerosis
    (Project Heads Drechsler, Maik ; Silvestre-Roig, Ph.D., Carlos ; Söhnlein, Oliver )
  - Regulatory role of non-coding RNAs and their homeostasis by autophagy in the progression of atherosclerosis
    (Project Heads Döring, Yvonne ; Mägdefessel, Lars ; Santovito, Donato ; Söhnlein, Oliver )
- Completed projects
  - Alarmins induce acute neutrophil mobilization
    (Project Heads Söhnlein, Oliver ; Weber, Christian )
  - Neutrophils regulate endothelial dysfunction in atherosclerosis
    (Project Head Söhnlein, Oliver )
  - Wirkungen von Antiarrhythmika auf klonierte native und mutierte spannungsgesteuerte Kaliumkanäle des Herzens
    (Project Heads Brosius, Jürgen ; Madeja, Michael ; Straub, Heidrun )
Major Research Instrumentation
- Completed projects
  - Microscope for multiplexed antibody-based imaging
  - Spectral 5-Laser Cell Sorter for BSL-2 specimens
CRC/Transregios
- Current projects
  - Central Task of the Collaborative Research Center
    (Project Head Söhnlein, Oliver )
  - Neutrophil education in peripheral vascular beds
    (Project Head Söhnlein, Oliver )
  - Organ-specific priming during granulopoiesis generates neutrophil subsets
    (Project Head Silvestre-Roig, Ph.D., Carlos )
  - TRR 332: Neutrophils: origin, fate and function
    (Spokesperson Söhnlein, Oliver )
  - Visualizing neutrophils in context
    (Project Heads Dreisewerd, Klaus ; Engel, Daniel Robert ; Söhnlein, Oliver )
Research Training Groups
- Completed projects
  - GRK 2220: Evolutionary Processes in Adaptation and Disease (RTG EvoPAD)
    (Spokesperson Kurtz, Joachim )

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