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Project Details

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Professor Dr. Axel Roers

Address Universitätsklinikum Heidelberg
Institut für Immunologie
Im Neuenheimer Feld 305
69120 Heidelberg

Projects

As Applicant
- Current projects
  - Control of high-affinity IgE responses to animal venoms by skin innate type 2 immunity (Research Units)
  - Service project: Single cell transcriptional profiling and bioinformatics (Research Units)
  - Coordination (Research Units)
- Completed projects
  - Analyse der Rolle von Interleukin-10 bei der Regulation von Immunantworten in der Haut mittels konditionaler Mutagenese des Interleukin-10- und des Interleukin-10-Rezeptor-Gens (Research Grants)
  - Kontrolle von Mastzellfunktionen bei entzündlichen Prozessen (Research Grants)
  - Interleukin-10-mediated cellular interactions in the regulation of cutaneous immune responses (Research Grants)
  - Role of NF-kappaB-dependent proinflammatory mast cell functions in immune responses (Research Grants)
  - Generation of breeders for setting up mutant mouse colonies by priority programme members (Priority Programmes)
  - Analyse des Pathomechanismus beim Aicardi-Goutières Syndrom im Tiermodell: Autoimmunität durch unkontrollierte Aktivität endogener Retroelemente? (Clinical Research Units)
As Leader
- Completed projects
  - Zellanalyse- und Hochgeschwindigkeits-Zellsortierungssystem (Major Research Instrumentation)
  - 2-Photonen Laser-Scanning Mikroskop für Intravital-Anwendungen (Major Research Instrumentation)
As Spokesperson
- Current projects
  - FOR 2599: Tissue type 2 responses: Mechanisms of induction and regulation (Research Units)
As Project Head
- Current projects
  - Molecular and cellular dynamics of nucleic acid-driven immune responses and immunopathology (CRC/Transregios)
  - Immune cell crosstalk in barrier-defective skin driving systemic atopic disease (CRC/Transregios)
- Completed projects
  - The role of interleukin-10 in the regulation of immune responses in the skin: Conditional mutagenesis of the interleukin-10- and the interleukin-10-receptior genes (Collaborative Research Centres)
  - Modulation of tissue regeneration by the glycosaminoglycan-binding anti-inflammatory cytokine interleukin-10 (CRC/Transregios)
  - Factors determining engraftment of transplanted hematopoietic stem cells (Collaborative Research Centres)
  - Core facility multi-photon intra-vital microscopy (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Impact of Mast cells on synovial inflammation and bone destruction in autoimmune-induced arthritis (Priority Programmes)
  - Role of mast cells in innate and adaptive immune response (Priority Programmes)

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