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Institution
Uniklinik Köln
Institut für Pathologie
Address
Kerpener Straße 62
50937 Köln
Deutschland
GERiT
This institution in GERiT
50937 Köln
Projects
Research Grants
Current projects
Tumor-specific endogenous immune response in esophago-gastric adenocarcinoma
(Applicant
Schlößer, Hans Anton
)
Understanding tumor progression and therapy resistance in Head and Neck Squamous Cell Carcinomas
(Applicants
Abedpour, Ph.D., Nima
;
George, Julie
)
Completed projects
Autophagic and Epigenetic Control of Liver-Directed Gene Therapy with Adeno-Associated Viral Vectors
(Applicants
Büning, Hildegard
;
Odenthal, Margarete
)
Deregulation von Zell-Matrix-Kontakten bei invasiven und metastatischen Melanomzellen; molekulare Funktion des Proteins MIA
(Applicant
Bosserhoff, Anja-Katrin
)
Epigenetic Impact on a Cancer Associated Signature of Alternative Splicing
(Applicant
Odenthal, Margarete
)
Esophageal adenocarcinoma: understanding the molecular basis of differential treatment response
(Applicants
Alakus, Hakan
;
Hillmer, Axel
;
Peifer, Martin
)
Funktion des Gens der autosomal-rezessiven polyzystischen Nierenerkrankung (ARPKD) in der Organogenese
(Applicant
Büttner, Reinhard
)
Funktionelle Analysen von Ets-Transkriptionsfaktoren sowie Ets-Fusionstranskripten in Prostatakarzinomen
(Applicant
Wernert, Nicolas
)
Funktionelle Charakterisierung des Transkriptionsfaktors AP-2 delta
(Applicants
Büttner, Reinhard
;
Moser, Markus
)
Genetische Mechanismen der Invasion und Metastasierung von Kolonkarzinomen
(Applicant
Büttner, Reinhard
)
Genexpressionsanalyse der Mesangialzellaktivierung
(Applicant
Fries, Jochen W.U.
)
microRNAs als prädiktive und prognostische Serummarker in der multimodalen Therapie des Ösophaguskarzinoms
(Applicant
Vallböhmer, Daniel
)
Regulation von Differnzierung und programmierten Zelltod neuraler und neuroektodermaler Systeme durch den Transkriptionsfaktor AP-2
(Applicant
Büttner, Reinhard
)
Understanding mechanisms of drug resistance and clonal evolution in diffuse large B cell lymphoma
(Applicant
Reinhardt, Christian
)
Priority Programmes
Completed projects
Deregulation von Zell-Matrix-Kontakten bei invasiven und metastatischen Melanomzellen; molekulare Funktion des Proteins MIA
(Applicant
Bosserhoff, Anja-Katrin
)
Collaborative Research Centres
Current projects
Multiparametric analysis of lymphoma cells and their microenvironment
(Project Heads
Büttner, Reinhard
;
Frenzel, Lukas
;
Oellerich, Thomas
;
Peltzer, Ph.D., Maria de las Nieves
;
Schweiger, Michal-Ruth
)
Predicting molecular mechanisms of adaptation to radio-chemotherapy in cancer
(Project Heads
Büttner, Reinhard
;
Hillmer, Axel
)
Predicting therapy response and relapse of aggressive B cell lymphomas
(Project Heads
Bozek, Katarzyna
;
Büttner, Reinhard
)
Proteogenomic characterization of mantle cell lymphoma
(Project Heads
Büttner, Reinhard
;
Oellerich, Thomas
)
Site-specific chronic inflammation and fibrosis in Fuchs endothelial corneal dystrophy
(Project Heads
Bachmann, Björn
;
Matthaei, Mario Magnus Goswin
;
Odenthal, Margarete
)
The influence of stroma-metastasis interaction on tumor evolution
(Project Heads
Beyer, Andreas
;
Hillmer, Axel
)
Translational Pathology Core
(Project Heads
Büttner, Reinhard
;
Quaas, Alexander
;
Schultheis, Anne M.
;
Siebolts, Udo
)
Completed projects
Diagnose, Staging und Grading von Tumoren und Festlegung der Zelltypspezifität - Nachweis von assoziierten Antigenen und Transkripten auf licht- und elektronenmikroskopischer Ebene sowie Genanalyse im Gewebe
(Project Head
Dienes, Hans-Peter
)
Histopathology platform for analysis of tumor microenvironment and immune cells infiltrates
(Project Heads
Büttner, Reinhard
;
Heukamp, Lukas Carl
;
Wardelmann, Eva
)
Oncogenic signaling pathways regulating invasive growth, metastasis and tumor microenvironment of small cell lung cancer (SCLC)
(Project Heads
Büttner, Reinhard
;
Heukamp, Lukas Carl
)
Predicting patterns of adaptation to radio-chemotherapy in cancer
(Project Head
Büttner, Reinhard
)
Zelltod beim Morbus Hodgkin
(Project Heads
Dienes, Hans-Peter
;
Hell, Karen
;
Lorenzen, Johann
)
Clinical Research Units
Completed projects
Aktivierung mesenchymaler Zellen durch FHL2-vermittelte Signaltransduktion bei intestinaler Reparatur
(Applicant
Kirfel, Jutta
)
Central diagnostics, genomics and biobanking
(Applicants
Büttner, Reinhard
;
Herling, Carmen Diana
;
Kreuzer, Karl-Anton
)
Research Fellowships
Completed projects
The impact of the transcription factor c-Jun on bone mass via the regulation of osteoprogenitor cells
(Applicant
Lerbs, Tristan
)
Major Research Instrumentation
Completed projects
Cell Sorter
CRC/Transregios
Completed projects
The impact of the LIM domain proteins FHL2 and CRP2 on hepatic stellate cell activation and its crosstalk with TGF-beta signalling pathways in hepatic fibrogenesis
(Project Heads
Büttner, Reinhard
;
Weiskirchen, Ralf
)
Research Training Groups
Completed projects
GRK 804: Analysis of Cellular Functions by Combinatorial Chemistry and Biochemistry
(Spokesperson
Famulok, Michael
)
Additional Information
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