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Institution

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Leibniz-Institut für Immuntherapie

Address Franz-Josef-Strauß-Allee 11
93053 Regensburg
Deutschland

GERiT This institution in GERiT

93053 Regensburg

Projects

Clinical Research Units
- Completed projects
Research Units
- Current projects
  - FOR 2858: Role of translocator protein (18 kDa) (TSPO) as a diagnostic and therapeutic target in the nervous system
    (Spokesperson Rupprecht, Rainer )
  - Multi-sample structural variant calling with linked-read sequencing data
    (Applicant Kehr, Birte )
  - The role of TSPO in T-cell immune control of glioblastoma
    (Applicants Beckhove, Philipp ; Hau, Peter )
- Completed projects
Research Grants
- Completed projects
Priority Programmes
- Current projects
  - Understanding how changes in spatial chromatin organization cause defective gene expression in acute myeloid leukemia with cohesin mutations.
    (Applicant Gebhard, Ph.D., Claudia )
Emmy Noether International Fellowships
- Completed projects
  - Molecular mechanism of memory-like regulatory T cells in autoimmune diabetes
    (Applicant Feuerer, Markus )
CRC/Transregios
- Current projects
  - Animal engineering and complex transplantation models
    (Project Heads Beilhack, Andreas ; Hoffmann, Petra ; Winkler, Thomas )
  - Data integration platform and systems medicine efforts to foster GvL and GvHD research
    (Project Heads Dandekar, Thomas ; Holler, Ernst ; Kehr, Birte ; Kunz, Meik )
  - Efficacy and safety of HLA-DPB1-specific T cell receptors as mediators of graft-versus-leukemia effect
    (Project Heads Herr, Wolfgang ; Thomas, Simone )
  - EMT-dependent transcriptional enhancers important for metastatic colonisation
    (Project Heads Brabletz, Simone ; Schmidl, Christian )
  - Functional role of fibroblast reticular cell-derived IL-33 in early metastasis
    (Project Heads Feuerer, Markus ; Hehlgans, Thomas )
  - GvHD therapy with in vitro expanded donor regulatory T cells
    (Project Heads Edinger, Matthias ; Hoffmann, Petra ; Rehli, Michael )
  - Harnessing tissue homeostasis-promoting functions of specialized regulatory T cells in graft-versus-host disease
    (Project Head Feuerer, Markus )
  - Timed targeting of cGAS / STING to improve tissue-regeneration and anti-tumor responses following allo-HSCT
    (Project Heads Poeck, Hendrik ; Schmidl, Christian )
  - TRR 221: Modulation of graft-versus-host and graft-versus-leukemia immune responses after allogeneic stem cell transplantation
    (Spokesperson Herr, Wolfgang )
- Completed projects
  - Targeting novel immune check points in multiple myeloma and acute myeloid leukemia to improve allogeneic hematopoietic stem cell transplantation
    (Project Head Beckhove, Philipp )
Major Research Instrumentation
- Completed projects
  - 5-Laser Flow Cytometer
  - 5-Laser Highspeed cell sorter
WBP Fellowship
- Current projects
  - Engineering safer theranostic CAR-T cells with a novel cytokine sensor-dependent therapeutic gene switch
    (Applicant Menevse, Ayse Nur )
Collaborative Research Centres
- Current projects
  - Collaborative Design of Exploratory DAWs in Neuroimaging
    (Project Heads Deniz, Ph.D., Fatma ; Kehr, Birte ; Weidlich, Matthias )
- Completed projects
  - Control of tumor-specific T cell responses through regulatory T cells
    (Project Heads Beckhove, Philipp ; Jäger, Dirk )

Subinstitutions

Abteilung für Gen-Immuntherapie

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