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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Medizinische Klinik und Poliklinik I - Allgemeine Innere Medizin
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Grants
Completed projects
Adenoviral- or bile acid-mediated transfer of therapeutic neucleid acids in hepatocytes to inhibit Hepatitis C in viral translation in vitro and in vivo
(Applicant
Caselmann, Wolfgang
)
Analysis and modification of the metabolic antioxidative balance as risk factor for liver fibrosis in humanized, transgenic UGT1A SNP and wild type mice
(Applicant
Strassburg, Christian
)
Immunmodulation durch induzierte Antigen-spezifische regulatorische T-Zellen bei der chronischen Hepatitis C Infektion
(Applicant
Spengler, Ulrich
)
Klinische Studien - Vorbereitungskosten
(Applicant
Sauerbruch, Tilman
)
Mediators of vascular inflammation and tertiary lymphoid organ formation in chronic kidney disease
(Applicant
von Vietinghoff, Sibylle
)
Modulation of dead cell disposal and inflammatory signaling as novel approach to peritoneal membrane preservation in dialysis
(Applicant
von Vietinghoff, Sibylle
)
Pathophysiologische Bedeutung der Gallensäure beta-Glukosidase (GBA2): Untersuchungen an GBA2-defizienten Mäusen, Mutationsanalysen von M. Gaucher Patienten am GBA2-Gen
(Applicants
van Echten-Deckert, Ph.D., Gerhild
;
Yildiz, Yildiz
)
Role of hepatic CD49a+ Natural Killer cells for hepatitis C virus infection
(Applicant
Krämer, Benjamin
)
The role of renal impairment in atherosclerotic inflammation
(Applicant
von Vietinghoff, Sibylle
)
Ttoxicity analyses and therapeutic modification of the anti-cancer drug camptothecin
(Applicant
Strassburg, Christian
)
Tumour associated microparticles as a novel biomarker in HCC and CCA
(Applicant
Kornek, Miroslaw
)
Urolithiasis: Entwicklung und Validierung eines massenspektrometrischen Verfahrens zur Messung der gastrointestinalen Oxalsäureabsorption
(Applicant
von Unruh, Gerd
)
Zytoprotektive und metabolische Rolle der UDP-Glukuronosyltransferasen (UGT) in der Karzinogenese gastrointestinaler Tumoren
(Applicant
Strassburg, Christian
)
Priority Programmes
Completed projects
Kombinierte CpG-Oligodeoxynukleotid/Lipopeptid Liposomen als neuer immunmodulatorischer Impfstoff gegen Hepatitis C Virus Infektion
(Applicant
Spengler, Ulrich
)
Regulation of functional heterogeneity and plasticity of human tissue-bound ILC3
(Applicant
Nattermann, Jacob
)
Heisenberg Fellowships
Completed projects
Experimentelle Gastroenterologie
(Applicant
Strassburg, Christian
)
Clinical Research Units
Completed projects
Charakterisierung der Rolle von Metabolisierungsenzym- und Transporter-Polymorphismen beim hepatozellulären Karzinom (HCC)
(Applicant
Strassburg, Christian
)
Research Units
Current projects
FOR 5427: BActerial Renal InfeCtion And DEfense (BARICADE)
(Spokesperson
Wagenlehner, Florian
)
Protection from pyelonephritis during glucosuria
(Applicant
von Vietinghoff, Sibylle
)
Collaborative Research Centres
Current projects
Myeloid immune cell subsets and the renal microenvironment in glomerulonephritis
(Project Heads
Kurts, Christian
;
von Vietinghoff, Sibylle
)
Completed projects
Regulation of immune functions by alternative antigen presentation in HIV and HCV infection
(Project Heads
Nattermann, Jacob
;
Spengler, Ulrich
)
The molecular basis and genetic variability of mucosal UDP-glukuronosyltransferase (UGT) gene regulation in humans and the humanized UGTIA-SNP-C57BL/6 mouse model
(Project Head
Strassburg, Christian
)
Research Fellowships
Completed projects
Induction of fibrolytic activity in hepatic stellate cells by T cell derived microparticles in vitro and in vivo
(Applicant
Kornek, Miroslaw
)
Regulation of neutrophil homeostasis by IL-17A and IL-17F-producing gamma-delta-T-cells
(Applicant
von Vietinghoff, Sibylle
)
CRC/Transregios
Completed projects
Angiotensin stimulated hepatic fibrogenesis and portal hypertension: Receptor regulation and intracellular signaling
(Project Heads
Sauerbruch, Tilman
;
Trebicka, Ph.D., Jonel
)
Regulation of Hepatic Carcinogen-metabolizing UGT1A Genes and HCC Development in the Humanized UHT1A-SNP Mouse
(Project Heads
Manns, Michael Peter
;
Strassburg, Christian
)
Role of innate lymphoid cells in liver fibrosis
(Project Heads
Nattermann, Jacob
;
Spengler, Ulrich
)
Clinical Trials
Completed projects
Covered transjugular intrahepatic portosystemic stent shunt versus optimezed medical treatment for the secondary prevention of variceal bleeding in cirrhosis
(Applicant
Sauerbruch, Tilman
)
Additional Information
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