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Institution

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Johannes Gutenberg-Universität Mainz
Universitätsmedizin Mainz
Klinik und Poliklinik für Neurologie

Address Langenbeckstraße 1
55131 Mainz
Deutschland

GERiT This institution in GERiT

55131 Mainz

Projects

Research Grants
- Current projects
  - Adrenergic Regulation of Spinal Neurons in Chronic Pain: Does the noradrenergic descending pain control system facilitate pain due to spinal reorganization under chronic pain conditions in mice?
    (Applicant Hirsch, Silke )
  - Health Literacy in patients with acute cerebral ischemic disease and organisational health literacy of a stroke-unit
    (Applicant Hahn, Marianne )
- Completed projects
CRC/Transregios
- Current projects
  - Disease-overarching mechanisms of Treg-CNS interaction
    (Project Heads Bittner, Stefan ; Liesz, Arthur )
- Completed projects
  - Balancing glutamate and cation channel signaling in inflammatory neuronal injury
    (Project Head Bittner, Stefan )
  - Central tasks / Administrative office of the SFB TRR 43
    (Project Heads Heppner, Frank ; Zipp, Frauke )
  - Clinical translational Unit
    (Project Heads Fleischer, Vinzenz ; Gold, Ralf ; Hemmer, Bernhard ; Hohlfeld, Reinhard ; Klotz, Luisa ; Kuhlmann, Tanja ; Kümpfel, Tania ; Lehmann-Horn, Klaus ; Lüssi, Felix ; Meyer zu Hörste, Gerd ; Wiendl, Heinz ; Zipp, Frauke )
  - Mechanisms and sites of neurodegeneration in chronic inflammation of the brain
    (Project Head Zipp, Frauke )
  - NfL and EGFL7 as biomarkers for neuroaxonal damage and BBB-integrity in neuroinflammation: A translational approach
    (Project Heads Uphaus, Timo ; Zipp, Frauke )
  - Rebalancing cortical neuronal hyperactivity as a new treatment strategy in Neuroinflammation
    (Project Heads Ellwardt, Erik ; Stroh, Albrecht ; Zipp, Frauke )
  - Spatiotemporal effects of IL-4 and designed novel compounds on CNS repair during neuroinflammation
    (Project Heads Vogelaar, Ph.D., Christina Francisca ; Zipp, Frauke )
  - Topological patterns of damage and compensation in chronic neuroinflammation
    (Project Heads Groppa, Sergiu ; Meuth, Sven G. ; Muthuraman, Ph.D., Muthuraman ; Zipp, Frauke )
  - Unraveling the role of myeloid cells and metabolism in clinical progression of MS
    (Project Heads Bittner, Stefan ; Bopp, Tobias ; Zipp, Frauke )
Clinical Research Units
- Completed projects
  - Kernspintomographische Untersuchungen elektrostatisch stabilisierter magnetischer Nanopartikel an enzephalitogenen T-Zellen und im Mausmodell der Multiplen Sklerose
    (Applicant Zipp, Frauke )
Clinical Trials
- Current projects
  - Intensive rhythm monitoring to decrease ischemic stroke and systemic embolism – the Find-AF 2 study
    (Applicant Wachter, Rolf )
Collaborative Research Centres
- Current projects
  - Immune Cytokines in the Regulation of Neuronal Homeostasis
    (Project Heads Kipnis, Jonathan ; Vogelaar, Ph.D., Christina Francisca ; Zipp, Frauke )
  - Modulation of glioma-neuron networks by immune cells in malignant brain tumors
    (Project Heads Schmidt, Mirko H.H. ; Zipp, Frauke )
- Completed projects
Research Units
- Current projects
  - FOR 2690: Translational Pruritus Research
    (Spokesperson Schmelz, Martin )
  - Transcriptomic patterns of dermal Schwann cell reactivity in neuropathic itch and pain
    (Applicants Birklein, Frank ; Schirmer, Lucas ; Sommer, Claudia )
Priority Programmes
- Current projects
  - Automated longitudinal characterization of the choroid plexus and glymphatic system in multiple sclerosis: facilitation of biomarker extraction and improvement of patient stratification
    (Applicants Gonzalez Escamilla, Ph.D., Gabriel ; Groppa, Sergiu ; Kronfeld, Andrea ; Mukhopadhyay, Ph.D., Anirban ; Othman, Ahmed )
Research Training Groups
- Completed projects
  - GRK 238: Mechanisms of Damage in CNS Disease - Application of Imaging Techniques
    (Spokesperson Heinemann, Uwe )
  - GRK 1044: Developmental and Disease-induced Modifications of the Nervous System
    (Spokesperson Luhmann, Heiko J. )

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