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Institution

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Goethe-Universität Frankfurt am Main
Universitätsklinikum
Zentrum für Molekulare Medizin
Institut für Kardiovaskuläre Regeneration

Address Theodor-Stern-Kai 7
60596 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60596 Frankfurt am Main

Projects

Research Grants
- Current projects
  - Inflammation-driven Diseases Program (INDEEP): inflammatory response as driver for human diseases and target for therapy
    (Applicant Ullrich, Evelyn )
- Completed projects
Research Units
- Current projects
- Completed projects
  - Molecular mechanisms underlying apoptosis and differentiation of circulating progenitor cells
    (Applicant Dimmeler, Stefanie )
  - Zentrale Aufgaben
    (Applicant Dimmeler, Stefanie )
Priority Programmes
- Completed projects
  - In vitro transdifferentiation of human endothelial progenitor cells into cardiac myocytes: determination of the underlying mechanisms
    (Applicant Dimmeler, Stefanie )
Collaborative Research Centres
- Current projects
  - Bioinformatics
    (Project Head Schulz, Marcel )
  - Damage-induced dynamics of the stromal compartment
    (Project Head de Luxan Garcia, Guillermo )
  - Endothelial plasticity and damage control
    (Project Head Dimmeler, Stefanie )
  - Reparative functions of endothelial cells in the aging heart
    (Project Heads Dimmeler, Stefanie ; Wagner, Julian )
  - Single Cell Technologies
    (Project Head Abplanalp, Ph.D., Wesley )
- Completed projects
  - Bedeutung der S-nitrosylierung von Proteinen bei der Apoptose von Endothelzellen: Charakterisierung der Denitrosylierung
    (Project Heads Dimmeler, Stefanie ; Rössig, Lothar )
  - Cell type-specific and stress-modulated microRNA target regulation
    (Project Head Dimmeler, Stefanie )
  - Fibroblast dynamics to mitigate tissue damage
    (Project Heads Cattaneo, Paola ; Guimarães Camboa, Nuno )
  - Integrated Research Training Unit "Vascular Biology and Medicine"
    (Project Head Dimmeler, Stefanie )
  - Long non-coding RNAs as regulators of endothelial cell function
    (Project Head Boon, Reinier )
  - Regulation der Mobilisierung von Stamm/Progenitorzellen durch NO
    (Project Heads Aicher, Alexandra ; Dimmeler, Stefanie )
  - Regulation of vascular repair and remodelling by non-coding RNAs
    (Project Heads Dimmeler, Stefanie ; Fichtlscherer, Stephan ; Vasa-Nicotera, Mariuca )
  - Role of JmjC domain-containing proteins in endothelial cell signaling and repair
    (Project Head Dimmeler, Stefanie )
CRC/Transregios
- Current projects
  - Bioinformatic analysis platform
    (Project Heads Gagneur, Julien ; Schulz, Marcel )
  - LncRNA control of cardiac inflammation
    (Project Heads Cremer, Sebastian ; Dimmeler, Stefanie ; Jaé, Nicolas )
  - Localisation-dependent function of lncRNAs in cardiovascular disease: from mechanism to phenotype
    (Project Head Dumbovic, Gabrijela )
  - Long non-coding RNAs in vascular ageing, remodeling, and abdominal aortic aneurysms
    (Project Heads Boon, Reinier ; Mägdefessel, Lars )
- Completed projects
  - Elucidating protein-RNA interactions in circRNA biogenesis and function
    (Project Heads Dimmeler, Stefanie ; Zarnack, Katharina )
  - RNA regulatory mechanisms in cardiac metabolism
    (Project Head Krishnan, Ph.D., Jaya )
  - Role of flow-induced microRNAs in vessel maturation
    (Project Head Dimmeler, Stefanie )
  - Role of integrin activity regulation for endothelial cell adhesion, migration and angiogenesis
    (Project Heads Chavakis, Emmanouil ; Dimmeler, Stefanie )
Research Training Groups
- Completed projects
  - GRK 1172: Research, Development and Safety of Biologicals
    (Spokesperson Pfeilschifter, Josef M. )
Clusters of Excellence
- Completed projects
  - EXC 115: Macromolecular Complexes
    (Spokespersons Dötsch, Volker ; Schwalbe, Harald )
  - EXC 147: Cardio-Pulmonary System
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner ; Zeiher, Andreas Michael )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2026: Cardio-Pulmonary Institute (CPI)
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner )

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