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Institution
Rheinische Friedrich-Wilhelms-Universität Bonn
Medizinische Fakultät
Klinik und Poliklinik für Anästhesiologie
und Operative Intensivmedizin
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Fellowships
Completed projects
Die Bedeutung von extrazellulärem Heat Shock Protein 60 (HSP60) für die proinflammatorische und proapoptotische Aktivität im Rahmen einer LPS-induzierten Myokarddepression
(Applicant
Kim, Se-Chan
)
Epithelial HIF and NFKB regulation during hypoxia and inflammation
(Applicant
Ehrentraut, Stefan
)
Gram-positive Sepsis: Bedeutung des Toll Like Rezeptors-2 für die Entstehung der septischen Kardiomyopathie
(Applicant
Knüfermann, Pascal
)
Novel mechanism for synergistic responses to systemic maternal inflammation and neonatal hyperoxia exposure on lung development and therapies to improve pulmonary function and reduce bronchopulmonary dysplaisa (BPD)
(Applicant
Velten, Markus
)
Role of HIF and induction of HIF-target genes during ventilator-induced lung injury
(Applicant
Ehrentraut, Heidi
)
Untersuchung der Wirkmechanismen stimulatorischer CpC Oligonukleotide (ODN) und suppressiver ODN an humanen Immunzellen
(Applicant
Klaschik, Sven
)
Untersuchungen zur relativen Sensitivität und Reliabilität von somatosensibel und motorisch evozierten Potentialen bei Operationen von Raumforderungen des craniospinalen Überganges, intraspinalen Prozessen und degenerativen Erkrankungen der Halswirbelsäule
(Applicant
Söhle, Martin
)
Research Grants
Current projects
The Role of Adaptive and Innate Immunity for the Development of Aortic Valve Stenosis
(Applicants
Hoyer, Friedrich Felix
;
Weisheit, Christina Katharina
;
Winkels, Holger
)
Completed projects
Argon: long term effects after transient middle artery occlusion; the role of ERK 1/2 activation; the effect on regional cerebral glucose metabolism on neuronal viability
(Applicant
Coburn, Mark
)
Detection of secondary neurodegeneration after subarachnoid hemorrhage in the rat using the PET tracer cis-4-[18F]fluoro-D-proline and functional MRI, and investigation of the neuroprotective effect of argon
(Applicants
Coburn, Mark
;
Shah, Ph.D., Nadim Jon
)
Die Einflüsse von erhaltener Spontanatmung während maschineller Beatmung auf die pulmonale Belüftung, die Ventilation und beatmungsassoziierte Entzündungsreaktion bei akutem Lungenversagen
(Applicant
Putensen, Christian
)
Differentielle Regulation der angeborenen Immunabwehr in einem myokardialen Second-Hit Modell
(Applicant
Baumgarten, Georg
)
Exzellenzakademie Medizintechnik für Nachwuchswissenschaftler "Monitoring and Computing in der perioperativen Medizin"
(Applicant
Hoeft, Andreas
)
Identification of molecular pharmacological mechanisms at human 5-HT3-receptors relevant to postoperative emesis
(Applicant
Urban, Bernd W.
)
Improving monitoring data utility in acute care medicine using mechanistic mathematical models of physiological processes
(Applicant
Zenker, Sven
)
Innate Immunity und Toll-Like rezeptor 9: Die Bedeutung von bakterieller DNA für die Entstehung der septischen Kardiomyopathie
(Applicant
Knüfermann, Pascal
)
Measuring regional lung ventilation/perfusion ratio using electrical impedance tomography
(Applicant
Putensen, Christian
)
Optimierung des Positiven End-Exspiratorischen Drucks (PEEP) bei akutem Lungenversagen mittels Elektrischer Impedanztomographie
(Applicant
Wrigge, Hermann
)
Perioperative Überwachung von Ventilation und Perfusion der Lunge mittels der elektrischen Impedanztomographie
(Applicant
Lüpschen, Henning
)
The role of ketogenesis in the immune response towards SARS-CoV-2
(Applicants
Bode, Christian
;
Wilhelm, Ph.D., Christoph
)
Clinical Trials
Current projects
Liberal transfusion strategy to prevent mortality and anaemia-associated, ischaemic events in elderly non-cardiac surgical patients (LIBERAL-Trial)
(Applicant
Meybohm, Patrick
)
Randomized, prospective, multicenter, open-label, controlled, parallel-group trial investigating the efficacy of add-on plasma-exchange as an adjunctive strategy against septic shock - 2 (EXCHANGE-2)
(Applicant
David, Sascha
)
CRC/Transregios
Current projects
Elucidation of the immune response and of the impact of the microbiome in murine calcific aortic valve stenosis
(Project Heads
Kurts, Christian
;
Weisheit, Christina Katharina
)
Completed projects
Activation of Hypoxia Inducible Factor 1 (HIF-1) transcriptional complex during retroviral infection and its role in immune activation
(Project Heads
Fandrey, Joachim
;
Frede, Stilla
)
Research Training Groups
Completed projects
GRK 246: Pathogenesis of Diseases of the Central Nervous System
(Spokesperson
Propping, Peter
)
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