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Institution

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Friedrich-Alexander-Universität Erlangen-Nürnberg
Nikolaus-Fiebiger Zentrum (NFZ)
Abteilung für Molekulare Immunologie

Address Glückstraße 6
91054 Erlangen
Deutschland

GERiT This institution in GERiT

91054 Erlangen

Projects

Research Grants
- Current projects
  - Regulation of plasma cell homeostasis and antibody secretion through modulation of autophagy and endoplasmic reticulum stress by Trk-fused-gene (TFG)
    (Applicant Mielenz, Dirk )
- Completed projects
  - Autumn School Current Concepts in Immunology
    (Applicant Jäck, Hans-Martin )
  - Structure of the pre-B cell receptor and its function during B cell maturation
    (Applicant Jäck, Hans-Martin )
  - Untersuchungen zur Liganden-vermittelten Initiierung von Prä-B-Zellrezeptorsignalen
    (Applicant Jäck, Hans-Martin )
Research Units
- Current projects
  - FOR 2886: PANDORA - Pathways triggering AutoimmuNity and Defining Onset of early Rheumatoid Arthritis
    (Spokesperson Krönke, Gerhard )
  - FOR 5560: Crosstalk between B cell metabolism and signaling
    (Spokesperson Jellusova, Julia )
  - The function of oxidative phosphorylation in early B cell development
    (Applicant Mielenz, Dirk )
- Completed projects
  - FOR 832: Regulators of the Humoral Immune Response
    (Spokesperson Winkler, Thomas )
  - Funktion des Krüppel-like Faktors 2 (KLF2) in der B-Zell-Homöostase und humoralen Immunantwort
    (Applicant Jäck, Hans-Martin )
  - Regulation der B-Zellaktivierung durch Swiprosin-1/EFhd2
    (Applicant Mielenz, Dirk )
  - The influence of mitochondrial lymphocyte metabolism on the onset of RA
    (Applicants Mielenz, Dirk ; Schett, Georg )
Collaborative Research Centres
- Completed projects
Priority Programmes
- Completed projects
  - How Fra/AP-1 transcription factors control the bone niche
    (Applicants Bozec, Ph.D., Aline ; Mielenz, Dirk )
  - Role for the bone environment in regulating immune responses
    (Applicant David, Ph.D., Jean-Pierre )
Major Research Instrumentation
- Completed projects
  - Hochgeschwindigkeits-Zellsorter mit 5 Lasern
CRC/Transregios
- Current projects
  - The protective role of eosinophils against inflammatory bone loss
    (Project Head Andreev, Darja )
- Completed projects
  - B cells and beyond
    (Project Heads Jäck, Hans-Martin ; Melchers, Fritz ; Schuh, Wolfgang )
  - Establishment of long-term humoral memory against SARS-CoV-2 after vaccination versus infection
    (Project Heads Jäck, Hans-Martin ; Winkler, Thomas ; Überla, Klaus )
  - The functions of EFhd1 and EFhd2 during checkpoints of early and terminal B cell differentiation
    (Project Head Mielenz, Dirk )
  - The role of the surface receptors IgA and EpCAM in plasma cell differentiation and maintenance
    (Project Heads Jäck, Hans-Martin ; Schuh, Wolfgang )
WBP Fellowship
- Completed projects
  - Characterize and unravel the phenotype of plasma cells in primary Sjögren Syndrome
    (Applicant Steinmetz, Tobit )
Research Training Groups
- Current projects
  - GRK 2599: FAIR - Fine-Tuners of the Adaptive Immune Response
    (Spokesperson Jäck, Hans-Martin )
- Completed projects
  - GRK 592: Lymphocytes: Differentiation, Activation and Deviation
    (Spokesperson Jäck, Hans-Martin )
  - GRK 1660: Key Signals of Adaptive Immune Response
    (Spokesperson Jäck, Hans-Martin )

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