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Institution
Friedrich-Alexander-Universität Erlangen-Nürnberg
Nikolaus-Fiebiger Zentrum (NFZ)
Abteilung für Translationale Immunologie
Address
Glückstraße 6
91054 Erlangen
Deutschland
GERiT
This institution in GERiT
91054 Erlangen
Projects
Research Grants
Completed projects
Autumn School Current Concepts in Immunology
(Applicant
Jäck, Hans-Martin
)
Regulation of plasma cell homeostasis and antibody secretion through modulation of autophagy and endoplasmic reticulum stress by Trk-fused-gene (TFG)
(Applicant
Mielenz, Dirk
)
Structure of the pre-B cell receptor and its function during B cell maturation
(Applicant
Jäck, Hans-Martin
)
Untersuchungen zur Liganden-vermittelten Initiierung von Prä-B-Zellrezeptorsignalen
(Applicant
Jäck, Hans-Martin
)
Research Units
Current projects
FOR 5560: Crosstalk between B cell metabolism and signaling
(Spokesperson
Jellusova, Julia
)
The function of oxidative phosphorylation in early B cell development
(Applicant
Mielenz, Dirk
)
Completed projects
FOR 832: Regulators of the Humoral Immune Response
(Spokesperson
Winkler, Thomas
)
FOR 2886: PANDORA - Pathways triggering AutoimmuNity and Defining Onset of early Rheumatoid Arthritis
(Spokesperson
Krönke, Gerhard
)
Funktion des Krüppel-like Faktors 2 (KLF2) in der B-Zell-Homöostase und humoralen Immunantwort
(Applicant
Jäck, Hans-Martin
)
Regulation der B-Zellaktivierung durch Swiprosin-1/EFhd2
(Applicant
Mielenz, Dirk
)
The influence of mitochondrial lymphocyte metabolism on the onset of RA
(Applicants
Mielenz, Dirk
;
Schett, Georg
)
Collaborative Research Centres
Completed projects
Allel-spezifische Regulation der HLA-Dy Expression und Relevanz für die Immungenetik des humanen Diabetes mellitus (Typ 1)
(Project Head
Waßmuth, Ralf
)
Mechanismen der Transduktion stimulatorischer und inhibitorischer Signale über die akzessorischen Moleküle CD28 und CTLA-4 auf T-Lymphozythen
(Project Heads
Manger, Bernhard
;
Nagel, Thomas
)
Rolle von Notch-1 bei Zelltypentscheidungen und apoptotischen Zelltodprozessen während der Reifung und Differenzierung B-lymphoider Zellen
(Project Heads
Jehn, Birgit
;
Jäck, Hans-Martin
)
Untersuchungen zum molekularen Mechanismus der durch den Prä-B-Zellrezeptor vermittelten Signaltransduktion in frühen B-lymphoiden Vorläuferzellen
(Project Head
Jäck, Hans-Martin
)
Priority Programmes
Completed projects
How Fra/AP-1 transcription factors control the bone niche
(Applicants
Bozec, Ph.D., Aline
;
Mielenz, Dirk
)
Role for the bone environment in regulating immune responses
(Applicant
David, Ph.D., Jean-Pierre
)
Major Research Instrumentation
Completed projects
Hochgeschwindigkeits-Zellsorter mit 5 Lasern
CRC/Transregios
Completed projects
B cells and beyond
(Project Heads
Jäck, Hans-Martin
;
Melchers, Fritz
;
Schuh, Wolfgang
)
Establishment of long-term humoral memory against SARS-CoV-2 after vaccination versus infection
(Project Heads
Jäck, Hans-Martin
;
Winkler, Thomas
;
Überla, Klaus
)
The functions of EFhd1 and EFhd2 during checkpoints of early and terminal B cell differentiation
(Project Head
Mielenz, Dirk
)
The role of the surface receptors IgA and EpCAM in plasma cell differentiation and maintenance
(Project Heads
Jäck, Hans-Martin
;
Schuh, Wolfgang
)
Fellowship
Completed projects
Characterize and unravel the phenotype of plasma cells in primary Sjögren Syndrome
(Applicant
Steinmetz, Tobit
)
Research Training Groups
Completed projects
GRK 592: Lymphocytes: Differentiation, Activation and Deviation
(Spokesperson
Jäck, Hans-Martin
)
GRK 1660: Key Signals of Adaptive Immune Response
(Spokesperson
Jäck, Hans-Martin
)
GRK 2599: FAIR - Fine-Tuners of the Adaptive Immune Response
(Spokespersons
Jäck, Hans-Martin
;
Zaiss, Mario M.
)
Additional Information
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