CECAD
Universitätsklinikum Köln (AöR)
Address
Kerpener Straße 62
50937 Köln
Deutschland
GERiT
This institution in GERiT
50937 Köln
Projects
Research Grants
Current projects
Circadian regulation of ion dynamics and ageing: implications for the rhythmic proteome.
(Applicant
Stangherlin, Alessandra
)
From simple to stratifying epithelia: unifying and diverging adhesive and mechanical principles
(Applicant
Niessen, Carien
)
NLRP3-dependent and -independent effects in microglial senescence
(Applicant
Ising, Christina
)
Stop-and-go: exploring canonical and non-canonical functions of autophagy at mammalian cortical en passant synapses
(Applicant
Kononenko, Natalia
)
Completed projects
Cadherin function in epidermal morphogenesis and barrier formation
(Applicant
Niessen, Carien
)
Molecular and genetic interaction of the polarity proteins Par3 and aPKC in skin carcinogenesis
(Applicants
Iden, Sandra
;
Niessen, Carien
)
Non-canonical role of macroautophagy in neurotrophin signalling and axonal homeostasis
(Applicant
Kononenko, Natalia
)
Role of Integrin-linked kinase in skin homeostasis and carcinogenesis
(Applicant
Wickström, Ph.D., Sara A.
)
Role of microglia in amyloid beta-induced tau cross-seeding and spread
(Applicant
Ising, Christina
)
Structural and functional regulation of cell-cell junctions in diabetic retina
(Applicant
Niessen, Carien
)
Priority Programmes
Completed projects
Mechanisms of junctional actin organization in epidermal morphogenesis and homeostasis
(Applicant
Niessen, Carien
)
Research Units
Current projects
Communication of mechanical cues to the stress response in epidermal cells
(Applicant
Niessen, Carien
)
FOR 2743: Mechanical Stress Protection
(Spokesperson
Höhfeld, Jörg
)
WBP Position
Current projects
Convergent mechanisms of longevity across mammalian species
(Applicant
Di Fraia, Ph.D., Domenico
)
Rewiring of Purkinje cell connectivity to enhance cerebellar functional recovery after injury
(Applicant
Pérez Revuelta, Ph.D., Laura
)
Collaborative Research Centres
Current projects
Contribution of microglia cell death to tau pathology in Alzheimer’s disease and other tauopathies
(Project Head
Ising, Christina
)
Data management, data mining and image analysis
(Project Heads
Beyan, Oya
;
Bozek, Katarzyna
)
Predicting therapy response and relapse of aggressive B cell lymphomas
(Project Heads
Bozek, Katarzyna
;
Büttner, Reinhard
)
The role of the autophagy-endolysosome system in Purkinje cell survival and the impact of its dysfunction on brain-wide motor circuits
(Project Heads
Kononenko, Natalia
;
Liebscher, Sabine
)
Completed projects
Context-dependent regulation of intercellular communication and polarity in skin carcinogenesis
(Project Heads
Iden, Sandra
;
Niessen, Carien
)
Metabolic control of skin morphogenesis, barrier function and development of diabetes associated skin complications
(Project Heads
Brüning, Jens Claus
;
Niessen, Carien
)
Regulation of epidermal morphogenesis and barrier function by intercellular junctions
(Project Head
Niessen, Carien
)
SFB 829: Molecular Mechanisms Regulating Skin Homeostasis
(Spokespersons
Krieg, Thomas
;
Niessen, Carien
)
The role of cadherin mediated cell-cell adhesion in the epidermis
(Project Head
Niessen, Carien
)
Ultrastructural and cell biological service project
(Project Heads
Bloch, Wilhelm
;
Mauch, Cornelia
;
Niessen, Carien
)
Zentrale Aufgaben des Sonderforschungsbereichs
(Project Heads
Krieg, Thomas
;
Niessen, Carien
)
Research Fellowships
Completed projects
Anti tau scFvs - new tools to better understand and treat Alzheimer's disease
(Applicant
Ising, Christina
)
Major Research Instrumentation
Completed projects
Atomic Force Microscope
Confocal Spinning-Disc Microscope
Clinical Research Units
Current projects
Alterations of slit diaphragm proteins and the pathogenesis of albuminuria and FSGS
(Applicants
Benzing, Thomas
;
Bozek, Katarzyna
)
Central mouse generation, phenotyping and imaging
(Applicants
Bozek, Katarzyna
;
Schauss, Astrid
)
KFO 329: Disease pathways in podocyte injury – from molecular mechanisms to individualized treatment options
(Spokesperson
Benzing, Thomas
)
Research Training Groups
Current projects
GRK 2550: Dynamic regulation of cellular protein localization
(Spokesperson
Riemer, Jan
)
Completed projects
GRK 1960: Neural Circuit Analysis on the Cellular and Subcellular Level
(Spokesperson
Büschges, Ansgar
)
International Research Training Groups
Current projects
GRK 3110: Tumor Heterogeneity and Genomic Instability in Lung Cancer – From Basic Mechanisms to Clinical Implications
(Spokesperson
Büttner, Reinhard
)
Clusters of Excellence (ExStra)
Current projects
EXC 2030: CECAD - Excellent in Aging Research
(Spokespersons
Benzing, Thomas
;
Hoppe, Thorsten
;
Niessen, Carien
)
Clusters of Excellence
Completed projects
EXC 229: Cellular Stress Responses in Aging-Associated Diseases
(Spokesperson
Brüning, Jens Claus
)
