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Institution
CECAD
Universitätsklinikum Köln (AöR)
Address
Kerpener Straße 62
50937 Köln
Deutschland
GERiT
This institution in GERiT
50937 Köln
Projects
Research Grants
Current projects
Circadian regulation of ion dynamics and ageing: implications for the rhythmic proteome.
(Applicant
Stangherlin, Alessandra
)
From simple to stratifying epithelia: unifying and diverging adhesive and mechanical principles
(Applicant
Niessen, Carien
)
NLRP3-dependent and -independent effects in microglial senescence
(Applicant
Ising, Christina
)
Stop-and-go: exploring canonical and non-canonical functions of autophagy at mammalian cortical en passant synapses
(Applicant
Kononenko, Natalia
)
Completed projects
Cadherin function in epidermal morphogenesis and barrier formation
(Applicant
Niessen, Carien
)
Molecular and genetic interaction of the polarity proteins Par3 and aPKC in skin carcinogenesis
(Applicants
Iden, Sandra
;
Niessen, Carien
)
Non-canonical role of macroautophagy in neurotrophin signalling and axonal homeostasis
(Applicant
Kononenko, Natalia
)
Role of Integrin-linked kinase in skin homeostasis and carcinogenesis
(Applicant
Wickström, Ph.D., Sara A.
)
Role of microglia in amyloid beta-induced tau cross-seeding and spread
(Applicant
Ising, Christina
)
Structural and functional regulation of cell-cell junctions in diabetic retina
(Applicant
Niessen, Carien
)
Priority Programmes
Completed projects
Mechanisms of junctional actin organization in epidermal morphogenesis and homeostasis
(Applicant
Niessen, Carien
)
Research Units
Current projects
Communication of mechanical cues to the stress response in epidermal cells
(Applicant
Niessen, Carien
)
FOR 2743: Mechanical Stress Protection
(Spokesperson
Höhfeld, Jörg
)
WBP Position
Current projects
Convergent mechanisms of longevity across mammalian species
(Applicant
Di Fraia, Ph.D., Domenico
)
Rewiring of Purkinje cell connectivity to enhance cerebellar functional recovery after injury
(Applicant
Pérez Revuelta, Ph.D., Laura
)
Collaborative Research Centres
Current projects
Contribution of microglia cell death to tau pathology in Alzheimer’s disease and other tauopathies
(Project Head
Ising, Christina
)
Data management, data mining and image analysis
(Project Heads
Beyan, Oya
;
Bozek, Katarzyna
)
Predicting therapy response and relapse of aggressive B cell lymphomas
(Project Heads
Bozek, Katarzyna
;
Büttner, Reinhard
)
The role of the autophagy-endolysosome system in Purkinje cell survival and the impact of its dysfunction on brain-wide motor circuits
(Project Heads
Kononenko, Natalia
;
Liebscher, Sabine
)
Completed projects
Context-dependent regulation of intercellular communication and polarity in skin carcinogenesis
(Project Heads
Iden, Sandra
;
Niessen, Carien
)
Metabolic control of skin morphogenesis, barrier function and development of diabetes associated skin complications
(Project Heads
Brüning, Jens Claus
;
Niessen, Carien
)
Regulation of epidermal morphogenesis and barrier function by intercellular junctions
(Project Head
Niessen, Carien
)
SFB 829: Molecular Mechanisms Regulating Skin Homeostasis
(Spokespersons
Krieg, Thomas
;
Niessen, Carien
)
The role of cadherin mediated cell-cell adhesion in the epidermis
(Project Head
Niessen, Carien
)
Ultrastructural and cell biological service project
(Project Heads
Bloch, Wilhelm
;
Mauch, Cornelia
;
Niessen, Carien
)
Zentrale Aufgaben des Sonderforschungsbereichs
(Project Heads
Krieg, Thomas
;
Niessen, Carien
)
Research Fellowships
Completed projects
Anti tau scFvs - new tools to better understand and treat Alzheimer's disease
(Applicant
Ising, Christina
)
Major Research Instrumentation
Completed projects
Atomic Force Microscope
Confocal Spinning-Disc Microscope
Clinical Research Units
Current projects
Alterations of slit diaphragm proteins and the pathogenesis of albuminuria and FSGS
(Applicants
Benzing, Thomas
;
Bozek, Katarzyna
)
Central mouse generation, phenotyping and imaging
(Applicants
Bozek, Katarzyna
;
Schauss, Astrid
)
KFO 329: Disease pathways in podocyte injury – from molecular mechanisms to individualized treatment options
(Spokesperson
Benzing, Thomas
)
Research Training Groups
Current projects
GRK 2550: Dynamic regulation of cellular protein localization
(Spokesperson
Riemer, Jan
)
Completed projects
GRK 1960: Neural Circuit Analysis on the Cellular and Subcellular Level
(Spokesperson
Büschges, Ansgar
)
International Research Training Groups
Current projects
GRK 3110: Tumor Heterogeneity and Genomic Instability in Lung Cancer – From Basic Mechanisms to Clinical Implications
(Spokesperson
Büttner, Reinhard
)
Clusters of Excellence (ExStra)
Current projects
EXC 2030: CECAD - Excellent in Aging Research
(Spokespersons
Benzing, Thomas
;
Hoppe, Thorsten
;
Niessen, Carien
)
Clusters of Excellence
Completed projects
EXC 229: Cellular Stress Responses in Aging-Associated Diseases
(Spokesperson
Brüning, Jens Claus
)
Additional Information
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