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Max-Planck-Institut für Multidisziplinäre Naturwissenschaften

Address Am Fassberg 11
37077 Göttingen
Deutschland

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37077 Göttingen

Projects

Research Grants
- Current projects
  - NanoVidere - Photochromic Layers for Nanoscopy
    (Applicant Schmidt, Andreas )
  - Thermodynamically consistent approach to structure formation from first principles
    (Applicant Godec, Aljaz )
- Completed projects
  - Catalytic Mechanism of Peptide Bond Formation on the Ribosome
    (Applicant Rodnina, Marina V. )
  - Comparative analysis of planarian regeneration
    (Applicant Rink, Jochen )
  - Computer simulation of the molecular mechanism of processivity in sugar-degrading enzymes
    (Applicant de Groot, Berend )
  - Functional mechanisms of specific proteins of pre-catalytic B complex spliceosomes in constitutive and alternative splicing
    (Applicants Lührmann, Reinhard ; Wahl, Markus C. )
  - Mechanism of selenoprotein synthesis in bacteria
    (Applicant Rodnina, Marina V. )
  - Molecular Mechanisms of tRNA Selection on the Ribosome
    (Applicant Rodnina, Marina V. )
  - Multiphotonen 4Pi-konfokale Mikroskopie und ihre Anwendung in der Biologie
    (Applicant Hell, Stefan W. )
  - Quality control of translation on the ribosome
    (Applicant Rodnina, Marina V. )
  - Receptor ligand binding: complex structure prediction and affinity evaluation
    (Applicants Böckmann, Rainer ; de Groot, Berend )
  - Si- and Ge-mullite single crystals doped with foreign cations
    (Applicant Fischer, Reinhard X. )
  - Untersuchungen zur strukturellen Dynamik der AAA+ ATPase p97 in unterschiedlichen funktionellen Zuständen
    (Applicant Chari, Ashwin )
Research Units
- Current projects
  - FOR 2518: Functional dynamics of ion channels and transporters - DynIon -
    (Spokesperson Benndorf, Klaus )
- Completed projects
Priority Programmes
- Current projects
  - Dissecting structural and functional cooperation between cis-regulatory elements in higher-order chromatin structures
    (Applicant Oudelaar, A. Marieke )
- Completed projects
Research Fellowships
- Completed projects
  - Mechanism of selenocysteine incorporation on the ribosome
    (Applicant Gromadski, Kirill )
Emmy Noether Independent Junior Research Groups
- Completed projects
  - NMR at ultra-fast MAS (above 100 kHz) for the study of beta barrel and alpha helical membrane proteins.
    (Applicant Andreas, Loren )
  - Non-equilibrium Fluctuations and Cooperativity in Single-Molecule Dynamics: Going Beyond Fluctuation Theorems and Large Deviation Theory: Thermodynamically consistent renewal networks for driven single-molecule dynamics with memory
    (Applicant Godec, Aljaz )
Heisenberg Grants
- Current projects
  - Hidden dynamics and collective phenomena in and out of equilibrium
    (Applicant Godec, Aljaz )
Collaborative Research Centres
- Current projects
  - Ensemble inference – new sampling algorithms and applications in structural biology
    (Project Heads de Groot, Berend ; Habeck, Michael ; Rudolf, Daniel )
  - Geometry and Bayesian statistics to reconstruct protein radical structures from ENDOR spectroscopy
    (Project Heads Bennati, Marina ; Huckemann, Stephan )
  - High-resolution structural and mechanistic analyses of spliceosomal complexes and other RNPs by cryo-EM
    (Project Head Stark, Holger )
  - Reversible Long-range PCET in Ribonucleotide Reductases
    (Project Heads Bennati, Marina ; Tittmann, Kai )
  - SFB 1565: Molecular mechanisms and interplay of gene expression processes
    (Spokesperson Bohnsack, Markus T. )
  - SFB 1633: Pushing Electrons with Protons – Unifying Multi-Electron Redox Catalysis by Proton-Coupled Electron Transfer
    (Spokesperson Schneider, Sven )
  - SFB 1690: Disease Mechanisms and Functional Restoration of Sensory and Motor Systems
    (Spokesperson Moser, Tobias )
  - Speed, accuracy and quality control of translation
    (Project Heads Rodnina, Marina V. ; Wohlgemuth, Ingo )
  - Statistical methods for reconstruction of continuous movements from cryo-EM data
    (Project Heads Habeck, Michael ; Stark, Holger )
  - The organization of the synaptic cytoskeleton
    (Project Heads D' Este, Elisa ; Hell, Stefan W. )
  - The role of the Mediator complex in the regulation of enhancer-promoter interactions and gene expression
    (Project Head Oudelaar, A. Marieke )
- Completed projects
  - Assembly und Kern-Cytoplasma-Transport von U snRNPs
    (Project Head Lührmann, Reinhard )
  - Biochemie der Protein-RNA- und RNA-RNA-Wechselwirkungen im Spleißosom
    (Project Head Lührmann, Reinhard )
  - Biosynthese und nucleo-cytoplasmatischer Transport von UsnPNPs
    (Project Head Lührmann, Reinhard )
  - Co-translational protein insertion into the bacterial plasma membrane
    (Project Head Rodnina, Marina V. )
  - Die Rolle von Forkhead-verwandten Genen in der Entwicklung des Säugernervensystems
    (Project Head Gruss, Peter )
  - Funktion U5snRNP-assoziierte ATP- bzw. GTP-bindender Proteine beim Prä-mRNA Spleißen
    (Project Heads Achsel, Tilmann ; Fabrizio, Patrizia ; Lührmann, Reinhard )
  - High-resolution fluorescence microscopy and integrative data analysis
    (Project Heads Hell, Stefan W. ; Lehnart, Stephan E. )
  - High-resolution structure determination of dynamic macromolecular complexes by cryo-EM
    (Project Head Stark, Holger )
  - Immunelektronenmikroskopisches Service-Labor
    (Project Heads Jahn, Reinhard ; Lührmann, Reinhard )
  - isoSTED microscopy within tissue
    (Project Heads Egner, Alexander ; Hell, Stefan W. )
  - Lipid-protein interactions underlying mechanosensitivity in K2P K+ channels
    (Project Head de Groot, Berend )
  - Molecular imaging of cardiac calcium release units
    (Project Heads Hell, Stefan W. ; Lehnart, Stephan E. )
  - Nanoscale observations of membrane dynamics
    (Project Heads Eggeling, Christian ; Hell, Stefan W. )
  - Probing membrane-peptide and membrane-protein interactions by high-field pulsed EPR spectroscopy
    (Project Head Bennati, Marina )
  - Ribosome dynamics in translation
    (Project Head Rodnina, Marina V. )
  - Statistical inference for molecules: How many, when and where?
    (Project Heads Hell, Stefan W. ; Munk, Axel )
  - Structural and dynamical studies of ß-strand-membrane proteins by liquid-/solid-state NMR spectroscopy
    (Project Heads Andreas, Loren ; Griesinger, Christian ; Lange, Adam ; Linser, Ph.D., Rasmus )
  - Structural dynamics of the yeast spliceosome during its activation and catalysis of splicing
    (Project Head Lührmann, Reinhard )
  - Structure and dynamics of the NPC permeability barrier
    (Project Heads Andreas, Loren ; Görlich, Dirk )
DIP Programme
- Completed projects
  - Alternative splicing: Evolution of splicing factors and their complex binding specificity - Implications to human disease
    (Applicants Lührmann, Reinhard ; Michaeli, Shulamit )
DFG Research Centres
- Completed projects
  - Central Administration
    (Project Heads Bähr, Matthias ; Hell, Stefan W. )
  - FZT 103: Molecular Physiology of the Brain
    (Spokespersons Bähr, Matthias ; Hell, Stefan W. ; Schild, Detlev )
Research Training Groups
- Current projects
  - GRK 2455: BENCh - Benchmark Experiments for Numerical Quantum Chemistry
    (Spokesperson Mata, Ricardo )
  - GRK 2984: Evolutionary Genomics: Consequences of Biodiverse Reproductive Systems (EvoReSt)
    (Spokesperson Hörandl, Elvira )
- Completed projects
  - GRK 242: Molecular Genetics of Development
    (Spokesperson Pieler, Tomas )
  - GRK 521: Protein-Protein Interactions during Intracellular Transport of Macromolecules
    (Spokesperson Doenecke, Detlef )
  - GRK 782: Spectroscopy and Dynamics of Molecular Aggregates, Chains, Coils and Networks
    (Spokesperson Suhm, Martin )
CRC/Transregios
- Current projects
  - TRR 274: Checkpoints of Central Nervous System Recovery
    (Spokespersons Flügel, Alexander ; Simons, Mikael Jakob )
International Research Training Groups
- Completed projects
  - GRK 1422: Metal Sites in Biomolecules: Structures, Regulation and Mechanisms
    (Spokesperson Diederichsen, Ulf )
Clusters of Excellence
- Completed projects
  - EXC 171: Microscopy at the Nanometer Range (within DFG Research Centre CMPB)
    (Spokespersons Rizzoli, Ph.D., Silvio-Olivier ; Schild, Detlev )
Graduate Schools
- Completed projects
  - GSC 226: Göttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB)
    (Spokesperson Ficner, Ralf )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2067: Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells (MBExC)
    (Spokespersons Cramer, Patrick ; Moser, Tobias ; Steinem, Claudia )

Subinstitutions

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