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Institution
Universität Ulm
Fakultät für Naturwissenschaften
Institut für Molekulare Endokrinologie der Tiere
Address
Helmholtzstraße 8/1
89081 Ulm
Deutschland
GERiT
This institution in GERiT
89081 Ulm
Projects
Research Grants
Current projects
Glucocorticoid-coordinated regulation of satellite cells and their microenvironment in skeletal muscle
(Applicant
Tuckermann, Jan
)
(Reversible) cellular and genomic alterations induced by long-term glucocorticoid treatment
(Applicants
Greulich, Franziska
;
Vettorazzi, Sabine
)
Together we are stronger: Adrenal hormones in concert orchestrate the resolution of inflammation
(Applicant
Vettorazzi, Sabine
)
Completed projects
A novel function of cyclin-dependent kinase 5 (Cdk5) in bone integrity - a potential therapeutic target to treat osteoporosis
(Applicant
Tuckermann, Jan
)
Crossing Barriers with bio-based Therapeutics
(Applicant
Otte, Ph.D., Kerstin
)
Glucocorticoids promote iron overload in immune cells and metabolic tissues
(Applicant
Vujic Spasic, Ph.D., Maja
)
Glukokortikoid-Rezeptor und PPARgamma-Mediierte Genmodulation Endotoxinaktivierter Monozyten und der Kontaktallergie in vivo
(Applicant
Spanbroek, Rainer
)
GR-AMPK - Crosstalk of Glucocorticoid Receptor and AMP-induced Kinase in macrophages during inflammation and tissue repair
(Applicant
Tuckermann, Jan
)
H-Ras, a new regulator of bone integrity - the mechanistic base of osteoporosis triggered by a constitutive active H-Ras GTPase
(Applicants
Cirstea, Ion Cristian
;
Tuckermann, Jan
)
Molecular and genetic characterization of the Sorting Nexin 10 R51Q mutation and other mutations, causing osteopetrosis in infancy in Palestinian clans
(Applicant
Tuckermann, Jan
)
Molecular functions of Shank2 and Shank3 in bone integrity and osteoporosis
(Applicants
Böckers, Tobias
;
Tuckermann, Jan
)
Molecular Synergism between Hormonal Signaling and Iron Homeostasis
(Applicant
Vujic Spasic, Ph.D., Maja
)
Novel anti-inflammatory mechanisms of the Glucocorticoid Receptor
(Applicant
Tuckermann, Jan
)
The ecdysteroid receptor: A key regulator in arthropod development. Inter and intra molecular receptor interactions "in vitro" and "in vivo"
(Applicant
Spindler-Barth, Margarethe
)
Priority Programmes
Completed projects
Cell type specific action of glucocorticoids in inflammation and bone integrity of rheumatoid arthritis
(Applicant
Tuckermann, Jan
)
Dissecting the osteoimmunological role of dickkopf-1 in arthritis and glucocorticoidinduced bone loss
(Applicants
Hofbauer, Lorenz C.
;
Rauner, Martina
)
Investigation of the role of the nuclear receptor NR4a1 during bone turnover and maintenance of the hematopoietic niche in the bone marrow
(Applicant
Krönke, Gerhard
)
Research Units
Current projects
FOR 5146: Defining the osteohepatic axis in the context of iron homeostasis - FerrOs
(Spokesperson
Rauner, Martina
)
Role of iron in bone metabolism of Hfe-hemochromatosis
(Applicant
Vujic Spasic, Ph.D., Maja
)
Major Research Instrumentation
Completed projects
High Content Analysis System
In vivo Micro Computertomograph für Kleinnager
Collaborative Research Centres
Current projects
Glucocorticoids influence Schwann cell and macrophage responses in a mouse model of peripheral nerve injury
(Project Heads
Meyer zu Reckendorf, Sofia
;
Vettorazzi, Sabine
)
Modulation of the macrophage/adipocyte interface in age-related insulin resistance by the Glucocorticoid Receptor
(Project Heads
Gebhardt, Christof
;
Tuckermann, Jan
)
Osteoblast differentiation-stage specific mechanisms of glucocorticoid action during fracture healing
(Project Heads
Ignatius, Anita
;
Tuckermann, Jan
)
Completed projects
Effects of impaired glucocorticoid receptor function in hemorrhagic shock-induced lung injury with pre-existing cigarette smoke-induced chronic obstructive pulmonary disease
(Project Heads
Vettorazzi, Sabine
;
Wepler, Martin
)
Effekte und Wirkmechanismen von Androgenen im arteriellen Gefäßsystem
(Project Heads
Hanke, Hartmut
;
Weidemann, Wolfgang
)
CRC/Transregios
Current projects
Cell-specific activation of glucocorticoids resolves inflammatory arthritis and prevents bone resorption
(Project Heads
Baschant, Ulrike
;
Tuckermann, Jan
)
Research Training Groups
Completed projects
GRK 1041: Molecular Diabetology and Endocrinology in Clinical Medicine
(Spokesperson
Böhm, Bernhard Otto
)
GRK 2203: Micro- and nano-scale sensor technologies for the lung
(Spokesperson
Ortmanns, Maurits
)
Additional Information
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