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Institution
Universitätsklinikum Jena
Klinik für Neurologie
Address
Am Klinikum 1
07747 Jena
Deutschland
GERiT
This institution in GERiT
07747 Jena
Projects
Priority Programmes
Current projects
A humanized mouse model to analyse the age-dependent impact of gut microbiota on microglial diversity in the brain
(Applicants
Frahm, Christiane
;
Kaleta, Christoph
;
Schmeer, Ph.D., Christian
)
Completed projects
Developmental significance of GABAergic depolarization for the functional maturation of the primary visual cortex
(Applicants
Holthoff, Knut
;
Hübner, Christian Andreas
;
Kiebel, Stefan
;
Kirmse, Knut
)
Mechanismen der Bcl-XL- und Erythropoietin-vermittelten Neuroprotektion und axonalen Regeneration
(Applicant
Isenmann, Stefan
)
Motor-cognitive dual task performance: a multidimensional approach
(Applicant
Bublak, Peter
)
Reaktionsformen der Mikroglia bei somatischer Gentherapie im Zentralnervensystem
(Applicant
Weller, Michael
)
Research Grants
Current projects
Interaction of GABAA-receptor function and network activity in the developing hippocampus
(Applicants
Holthoff, Knut
;
Kirmse, Knut
)
Investigating humoral autoimmunity against the NMDA receptor GluN1 subunit by super-resolution fluorescence microscopy: effects on synapse integrity and function
(Applicants
Doose, Sören
;
Geis, Christian
)
Organ Dysfunction in Old Age: Perspectives for Young Clinician Scientists (OrganAge)
(Applicant
Witte, Otto Wilhelm
)
Role of tangential migration for cortical network maturation
(Applicants
Holthoff, Knut
;
Kirmse, Knut
;
Stumm, Ralf
)
Completed projects
A probabilistic fiber atlas of the human brainstem
(Applicant
Axer, Hubertus
)
Beteiligung von Connexin43 am Prozess der reaktiven Astrogliose nach fokaler zerebraler Ischämie
(Applicant
Frahm, Christiane
)
Biological significance of microgliae infiltration in malignant brain tumors
(Applicant
Weller, Michael
)
Cellular signalling mechanisms in the developing visual cortex
(Applicant
Holthoff, Knut
)
Epigenome-Microbiome crosstalk: A new way to maintain cognition at old age
(Applicants
Frahm, Christiane
;
Hoffmann, Steve
;
Kaleta, Christoph
)
Feature-specific BrainAGE profiles in middle and late adulthood: Investigating the relationships between individual body, brain, and cognitive aging
(Applicant
Franke, Katja
)
Impact of intracellular chloride-dependent modulation of radial glia-like stem cells on hippocampal neurogenesis and the associated cognitive function in the aging brain
(Applicant
Keiner, Silke
)
Pathomechanisms of autoantibody-induced autoimmunity to AMPA receptors
(Applicant
Geis, Christian
)
Prächirurgische Diagnostik extramesiotemporaler epileptischer Foci: bildgebende und neuropsychologische Prädiktoren für postoperative Hirnfunktionen
(Applicant
Ebner, Alois
)
Prächirurgische Diagnostik extramesiotemporaler epileptischer Foci: bildgebende und neuropsychologische Prädiktoren für postoperative Hirnfunktionen
(Applicant
Witte, Otto Wilhelm
)
Role of glial cell damage in onset and progression of neuronal degeneration after retinal ischemia and putative strategies for neuroprotection
(Applicant
Schmeer, Ph.D., Christian
)
Research Units
Current projects
Coordination Funds
(Applicant
Geis, Christian
)
Direct and acute effects of human monoclonal anti-GluN1 autoantibodies on NMDA receptor channel function
(Applicants
Geis, Christian
;
Heckmann, Manfred
)
FOR 3004: Synaptic pathology in autoimmune encephalitis – SYNABS
(Spokesperson
Geis, Christian
)
Molecular mechanisms and in-vivo functional effects of antibodies in GABAB receptor autoimmune encephalitis
(Applicants
Geis, Christian
;
Kornau, Hans-Christian
;
Schmidt-Hieber, Christoph
)
Completed projects
FOR 2293: Active Perception
(Spokesperson
Müller, Hermann J.
)
Impact of heme and heme degradations products on cerebral vascular reactibility
(Applicant
Witte, Otto Wilhelm
)
Project C1. Aging and the effect of predictivity and utility on perception
(Applicants
Finke, Kathrin
;
Sorg, Christian
)
Störungen raum-zeitlicher Integrationsleistungen in visuellen Suchaufgaben bei Patienten mit fronto-parietalen Läsionen
(Applicant
Bublak, Peter
)
Collaborative Research Centres
Completed projects
Mechanismen synaptischer Ca2+-Signale in zentralen Neuronen
(Project Heads
Holthoff, Knut
;
Konnerth, Arthur
)
Neuronale Dysfunktion und Hyperexcitabilität als Folge fokaler Hirnläsionen
(Project Heads
Witte, Otto Wilhelm
;
Zilles, Karl
)
Neurophysiologische Analyse kortikaler Aktivität bei normaler Funktion und läsionsinduzierter Störung des zentralen sensomotorischen Systems
(Project Heads
Freund, Hans-Joachim
;
Schnitzler, Alfons
;
Witte, Otto Wilhelm
)
Störungen der zerebralen zellulären Volumenregulation: Ursachen, funktionelle Konsequenzen und Bedeutung für die hepatische Enzephalopathie
(Project Head
Witte, Otto Wilhelm
)
Zelluläre und molekulare Grundlagen von Regenerationsvorgängen im ZNS
(Project Heads
Bähr, Matthias
;
Isenmann, Stefan
)
Major Research Instrumentation
Completed projects
Confocal-Laser-Scanning-Microscope
Hochfeld Kleintier MRT
Konfokales Laserscanning-Mikroskop
Research Fellowships
Completed projects
Quantification of Gyrification of the Brain
(Applicant
Dahnke, Robert
)
CRC/Transregios
Completed projects
Interaction of GABAA-receptor function and network activity in the developing hippocampus
(Project Heads
Holthoff, Knut
;
Kirmse, Knut
)
Investigating humoral autoimmunity against the NMDA-receptor NR1 subunit by super-resolution fluorescence microscopy: effects on synapse integrity and function
(Project Heads
Doose, Sören
;
Geis, Christian
)
Research Training Groups
Completed projects
GRK 320: Pathological Processes of the Nervous System: From Gene to Behavior
(Spokesperson
Reifenberger, Ph.D., Guido
)
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