Go directly to content
Go directly to font size and contrast
Servicenavigation
DFG Homepage
Disclaimer / Copyright
|
Help
|
Data Monitor
Deutsch
Hauptnavigation
Search
Catalogue
People Index
Location Index
About GEPRIS
Project Details
Back
Institution
Albert-Ludwigs-Universität Freiburg
Institut für Experimentelle & Klinische Pharmakologie und Toxikologie
Abteilung I
Address
Albertstraße 25
79104 Freiburg
Deutschland
GERiT
This institution in GERiT
79104 Freiburg
Projects
Priority Programmes
Completed projects
Deamidierung und Transglutaminierung von Rho GTPasen durch das dermonekrotische Toxin (DNT) von Bordetella bronchiseptica
(Applicant
Aktories, Klaus
)
Die Rolle von Rho-Proteinen in Fc epsilon-Ri-vermittelter Signaltransduktion
(Applicant
Aktories, Klaus
)
Koordination des Schwerpunktprogramm "Signalwege zum Zytoskelett und bakterielle Pathogenität"
(Applicant
Aktories, Klaus
)
Mode of action of Yersinia enterocolitica "outer protein" T (Yop T)
(Applicant
Schmidt, Gudula
)
SPP 1150: Signal Pathways to the Cytoskeleton and Bacterial Pathogenesis
(Spokesperson
Aktories, Klaus
)
Research Grants
Current projects
Cellular uptake of the Rho-activating toxins CNF1 and CNFY and of further deamidases
(Applicant
Schmidt, Gudula
)
Metastasis predisposing extracellular matrix architecture in colorectal cancer (PredisposAL)
(Applicants
Briquez, Ph.D., Priscilla
;
Fichtner-Feigl, Stefan
;
Reuten, Raphael
)
Photorhabdus Toxin Complex (PTC) as variable protein injection apparatus
(Applicant
Schmidt, Gudula
)
The Role of Septins in Cilia-Targeted Traffic
(Applicant
Schwan, Carsten
)
Two-pore channels (TPCs): NAADP-activation mechanisms and function for intracellular transport processes
(Applicant
Klugbauer, Norbert
)
Completed projects
Actin-ADP-ribosylierende Toxine und Mikrotubuli
(Applicant
Aktories, Klaus
)
ADP-Ribosylierung von RhoE/Rnd3 durch die Staphylococcus aureus ADP-Ribosyltransferase C3stau1
(Applicant
Aktories, Klaus
)
Biological activity and mode of action of the pasteurella multocida toxin
(Applicant
Aktories, Klaus
)
Biologische Funktion und Signaltransduktion von EDG-Rezeptoren in dendritischen Zellen
(Applicant
Norgauer, Johannes
)
Charakterisierung des ADP-ribosylierenden Bacillus sphaericus Toxins MTX
(Applicant
Aktories, Klaus
)
Effector glycosyltransferases of the human pathogen Legionella pneumophila
(Applicant
Aktories, Klaus
)
Expression des Proenkephalin Gens im Striatum - neuronale Interaktionen und Signaltransduktion
(Applicant
Meyer, Dieter Klaus
)
Glucosylierung durch clostridiale Zytotoxine: Enzymaktivität, Substraterkennung und Auffindung kleinmolekularer Inhibitoren
(Applicant
Aktories, Klaus
)
Glucosylierung von Elongationsfaktor eEF1A durch Legionella pneumophila Glucosyltransferase Lgt1
(Applicant
Aktories, Klaus
)
Identification and characterization of cell membrane receptors of binary actin-ADP-ribosylating toxins
(Applicant
Aktories, Klaus
)
Influence of Rho acitvating bacterial toxins on the regulation of Rho GTPase signaling networks
(Applicant
Schmidt, Gudula
)
Interaction of phosphoinositide 3-kinase and Rho GTPases during dendritic differentiation
(Applicant
Leemhuis, Jost
)
Involvement of heterotrimeric G proteins in bone atrophy caused by Pasteurella multocida toxin
(Applicant
Aktories, Klaus
)
Kindlins and Rho GTPase-mediated signaling pathways
(Applicants
Has, Cristina
;
Schmidt, Gudula
)
Modification of elongation factor eEF1A by Legionella pneumophila Lgt glucosyltransferases
(Applicant
Aktories, Klaus
)
Molekulare Mechanismen der Regulation der zellulären Migration durch L- Typ Calciumkanäle und deren Beeinflussung durch PI3-Kinasen und Rho GTPasen
(Applicant
Klugbauer, Norbert
)
NAD+-abhängige Transferasen und deren Inhibitoren
(Applicants
Aktories, Klaus
;
Jung, Manfred
;
Sippl, Wolfgang
)
Protein toxin complexes of Photorhabdus luminescens
(Applicant
Aktories, Klaus
)
Regulation und Struktur-Funktionsanalyse der GAP-Domäne von Pseudomonas aeruginosa Exoenzym S
(Applicant
Schmidt, Gudula
)
Structure-function analysis of large clostridial cytotoxins
(Applicant
Aktories, Klaus
)
Struktur-Funktions-Analyse "großer" clostridialer Zytotoxine
(Applicant
Hofmann, Fred
)
Untersuchungen zur Funktion von TPC1 Kanälen
(Applicant
Klugbauer, Norbert
)
Zelluläre Aufnahme der Rho aktivierenden Toxine CNF1 und CNFY
(Applicant
Schmidt, Gudula
)
Collaborative Research Centres
Completed projects
ADP-Ribosylierung von Aktin
(Project Head
Aktories, Klaus
)
ADP-Ribosylierung von Aktin durch bakterielle Toxine
(Project Heads
Aktories, Klaus
;
Barth, Holger
)
Minor splicing generates tumorigenic Rac variants in prostate cancer
(Project Heads
Aktories, Klaus
;
Schmidt, Gudula
)
Modification of GTP-binding proteins by deamidating and glycosylating toxins
(Project Heads
Aktories, Klaus
;
Jank, Thomas
;
Orth, Joachim
)
Modifikation von GTPasen durch bakterielle Toxine
(Project Heads
Aktories, Klaus
;
Schmidt, Gudula
)
Modifikation von "kleinen" GTP-bindenden Proteinen durch bakterielle ADP-Ribosyltransferasen
(Project Head
Aktories, Klaus
)
SFB 780: Synaptic Mechanisms of Neuronal Network Function
(Spokespersons
Jonas, Peter
;
Klugbauer, Norbert
)
Structure, function and regulation of toxin-induced microtubule-based cell protrusions
(Project Heads
Aktories, Klaus
;
Schwan, Carsten
)
Struktur und Funktion neuronaler spannungsabhängiger Kalziumkanäle
(Project Head
Klugbauer, Norbert
)
The function of presynaptic Cav2 Ca2+ channels
(Project Head
Klugbauer, Norbert
)
Untersuchungen der NMDA Rezeptor Unterheinheiten und Rho GTPasen, die an der Bildung des Dendritenbaumes beteiligt sind
(Project Heads
Leemhuis, Jost
;
Meyer, Dieter Klaus
)
Zelluläre Aufnahme von Aktin-ADP-ribosylierenden Toxinen
(Project Head
Aktories, Klaus
)
CRC/Transregios
Completed projects
Proteomic analysis and physiological function of the two pore channel TPC1
(Project Heads
Klugbauer, Norbert
;
Schulte, Uwe
)
Research Training Groups
Completed projects
GRK 843: Mechanisms of neuronal signal transduction - from protein to network
(Spokesperson
Fakler, Bernd
)
Additional Information
© 2024
DFG
Disclaimer / Copyright
/
Privacy Policy
Textvergrößerung und Kontrastanpassung
