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Institution
Universitätsklinikum Leipzig AöR
Klinik und Poliklinik für Endokrinologie, Nephrologie und Rheumatologie
Address
Liebigstraße 20
04103 Leipzig
Deutschland
GERiT
This institution in GERiT
04103 Leipzig
Projects
Research Grants
Current projects
A novel regulator of metabolic disease
(Applicant
Alexaki, Vasileia Ismini
)
Assessing genetic risk of post-kidney transplantation malignancy - a pilot study (KTx-Cancer)
(Applicant
Halbritter, Jan
)
MD-LEICS – Modern Diseases – Leipzig Clinician Scientist program
(Applicant
Ebert, Thomas
)
Metabolic signatures and neurophysiological mechanisms of bad food decisions.
(Applicants
Kovacs, Peter
;
Pauls, Dennis
)
Completed projects
Charakterisierung von Biosynthese, Trafficking und Metabolismus des extrazellulären Calcium-Sensing Rezeptors (CaR) im heterologen und autologen Zellsystem
(Applicant
Stumvoll, Michael
)
Differenzierung molekularer Determinanten der G-Protein Selektivität des TSH-Rezeptors als Perspektive für neue Therapieansätze
(Applicants
Krause, Gerd
;
Paschke, Ralf
)
Fettzellen als pathogenetischer Faktor der endothelialen Dysfunktion bei Adipositas und Diabetes mellitus
(Applicant
Fasshauer, Mathias
)
Functional crosstalk of BMP and Insulin signaling within glucose metabolism of adipocytes
(Applicant
Knaus, Petra
)
Funktion und Struktur von rezeptorinternem Transmitter (rIT) und multipler intramolekularer Aktivierungsmechanismus des TSH-Rezeptors
(Applicants
Krause, Gerd
;
Paschke, Ralf
)
Heterogenität des Fettgewebes - Parallel-Studien in Mausmodellen und beim Menschen
(Applicant
Blüher, Ph.D., Matthias
)
Identifizierung eines rezeptorinternen endogenen stillen Transmitters (RIT) im TSh-Rezeptor
(Applicant
Paschke, Ralf
)
MicroRNA 29b-dependent mechanisms of arterial stiffness in diabetes.
(Applicant
Schellinger, Isabel Nahal
)
MicroRNA signature of thyroid tumors and its possible diagnostic application for the differential diagnosis of follicular thyroid cancer and follicular adenomas
(Applicant
Eszlinger, Markus
)
Molekulargenetik der diabetischen Nephropathie
(Applicant
Lindner, Tom H.
)
Phänotypisierung der Defekte der Insulinsekretion bei Nachkommen von Typ 2 Diabetikern
(Applicant
Fritsche, Andreas
)
Rolle von Vaspin in der Pathogenese von Typ 2 Diabetes und Adipositas
(Applicant
Kovacs, Peter
)
Studie der Molekularbiologie der TSH-Rezeptor-Aktivierung
(Applicant
Paschke, Ralf
)
Understanding the significance of thyroid hormones in the context of adipocyte lineage determination by the transcription factor Zfp423.
(Applicant
Krause, Kerstin
)
Untersuchungen zum Zusammenwirken von TSH-Rezeptor und G-Proteinen bei der Signaltransduktion in der Schilddrüsenzelle
(Applicant
Holzapfel, Hans-Peter
)
Heisenberg Fellowships
Completed projects
Innere Medizin
(Applicant
Stumvoll, Michael
)
Research Units
Completed projects
Genetische Prädisposition für Typ-2 Diabetes in Deutschland
(Applicant
Lindner, Tom H.
)
Molecular genetics of type 2 diabetes (T2DM) in Germany: Genes / Polymorphisms fDeutschlands, die zur Entwicklung des Typ-2-Diabetes beitragen
(Applicant
Wichmann, Heinz-Erich
)
Molecular genetics of type 2 diabetes (T2DM) in Germany: Genes / Polymorphisms for T2DM - Cloning of diabetes susceptibility sequence variants
(Applicant
Lindner, Tom H.
)
Clinical Research Units
Completed projects
Atherobesity: Fett und Gefäß
(Applicant
Stumvoll, Michael
)
Chronische inflammatorische Aktivierung im Fettgewebe bei Adipositas: ein atherogener Faktor?
(Applicant
Linke, Axel
)
Heterogenität des Fettgewebes: Molekulare Mechanismen der viszeralen Fettakkumulation
(Applicant
Blüher, Ph.D., Matthias
)
KFO 152: Atherobesity: Adipose Tissue and Vasculature
(Spokesperson
Stumvoll, Michael
)
Rolle von Repin 1 in der Pathogenese der Adipositas
(Applicant
Klöting-Blüher, Nora
)
Priority Programmes
Completed projects
Definition of central and cellular effects of thyroid hormones on white adipose tissue browning
(Applicant
Krause, Kerstin
)
The relevance of thyroid hormones for the transdifferentiation of white into brown adipose tissue
(Applicant
Tönjes, Anke
)
Collaborative Research Centres
Current projects
Adipokines as modulators of cardiovascular function
(Project Heads
Fasshauer, Mathias
;
Laufs, Ulrich
;
Tönjes, Anke
)
Central Task of the Collaborative Research Center
(Project Head
Blüher, Ph.D., Matthias
)
Hormonal regulators of adipose tissue plasticity
(Project Head
Krause, Kerstin
)
How do xenobiotics affect adipose tissue function and distribution?
(Project Heads
von Bergen, Martin
;
Blüher, Ph.D., Matthias
)
Relationship of leaky gut-derived bacterial translocation and genetic regulation of body fat distribution
(Project Head
Kovacs, Peter
)
SFB 1052: Obesity Mechanisms
(Spokesperson
Blüher, Ph.D., Matthias
)
Targeting the brain through the gut: bottom-up mechanisms of eating behavior
(Project Heads
Stumvoll, Michael
;
Villringer, Arno
;
Witte, Veronica
)
Completed projects
Genetic Modulators of Serum Adipokine Concentrations
(Project Heads
Stumvoll, Michael
;
Tönjes, Anke
)
Research Fellowships
Completed projects
Discovery and functional characterization of novel single-gene causes and genetic modifiers in nephronophthisis
(Applicant
Petzold, Friederike
)
WBP Fellowship
Current projects
Identification of therapeutically exploitable targets contributing to weight loss and metabolic disease improvement after metabolic surgery in the microbiota-host-interactome
(Applicant
Chakaroun, Rima
)
Completed projects
Identifying novel therapeutic targets for lipotoxicity-driven kidney diseases
(Applicant
Sewerin, Sebastian
)
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