Ludwig-Maximilians-Universität München (LMU)
Biomedizinisches Centrum
Munich Cluster for Systems Neurology (SyNergy)
Address
Feodor-Lynen-Straße 17
81377 München
Deutschland
GERiT
This institution in GERiT
81377 München
Projects
Research Grants
Current projects
Dissecting the molecular function of TECPR2
(Applicant
Behrends, Ph.D., Christian
)
Exploring non-canonical functions of human ATG8 proteins
(Applicant
Behrends, Ph.D., Christian
)
Investigating the novel functions of Rab24 in mitochondrial fission and protein secretion
(Applicants
Behrends, Ph.D., Christian
;
Zeigerer, Ph.D., Anja
)
The molecular response to endolysosomal damage and its regulation by ubiquitylation and VCP/p97
(Applicants
Behrends, Ph.D., Christian
;
Meyer, Hemmo
)
Completed projects
Die biologische und pathologische Funktion der proteolytischen Prozessierung der Alzheimer relevanten Preseniline.
(Applicant
Haass, Christian
)
Functional dissection of ARIH1 E3 ubiquitin ligase in cellular antimicrobial immunity
(Applicants
Alpi, Ph.D., Arno
;
Behrends, Ph.D., Christian
)
Funktionelle Klonierung Alzheimer relevanter Proteasen
(Applicant
Haass, Christian
)
Mechanisms and Function of Intramembrane Proteolysis by the gramme-Secretase homologous Signal Peptide Peptidase-like Proteases (SPPL)
(Applicant
Haass, Christian
)
Molekulare Biologie und Pathologische Funktion von alpha-Synuclein bei der familiär vererbten Parkinson Erkrankung
(Applicant
Haass, Christian
)
Reduktion der Amyloid-Plaque Akkumulation durch mikrogliale Neprilysin-Expression in einem transgenen Mausmodell der Alzheimer Pathologie
(Applicant
Haass, Christian
)
Emmy Noether Independent Junior Research Groups
Completed projects
Molecular dissection of the human autophagy signaling pathway
(Applicant
Behrends, Ph.D., Christian
)
Research Units
Completed projects
FOR 2290: Understanding Intramembrane Proteolysis
(Spokesperson
Langosch, Dieter
)
Functional role of transmembrane domain interactions and intramembrane cleavage of microglial innate immunity receptors
(Applicant
Haass, Christian
)
Reinhart Koselleck Projects
Completed projects
TREM2 dependent microglial function and dysfunction: A target for therapeutic modulation of Alzheimer's disease and Frontotemporal Dementia
(Applicant
Haass, Christian
)
Heisenberg Grants
Current projects
Unraveling molecular mechanisms of the preferential degeneration of midbrain neurons in neurodegenerative diseases
(Applicant
Burbulla, Lena
)
Priority Programmes
Completed projects
Molecular Mechanisms of Presenilin Function
(Applicant
Haass, Christian
)
SPP 1085: Cellular Mechanisms of Alzheimer's Disease
(Spokespersons
Haass, Christian
;
Multhaup, Gerhard
)
The cellular basis of APP processing: trafficking and assembly of gamma-secretases and its substrates
(Applicant
Haass, Christian
)
Collaborative Research Centres
Current projects
Molecular analysis of physiological and BPAN-related WIPI4 functions
(Project Heads
Behrends, Ph.D., Christian
;
Proikas-Cezanne, Tassula
)
Quantitative proteomics and integrated systems biology
(Project Heads
Behrends, Ph.D., Christian
;
Beli, Petra
;
Bhaskara, Ph.D., Ramachandra M.
;
Dikic, Ivan
;
Hummer, Gerhard
;
Münch, Christian
)
Completed projects
Administration, Travel, Meetings and Seminars of the Collaborative Research Centre
(Project Head
Haass, Christian
)
Functional Analysis of ß-secretase (Bace) and Regulation of subcellular Trafficking
(Project Head
Haass, Christian
)
Functional Characterization of y-Secretase
(Project Heads
Haass, Christian
;
Steiner, Harald
)
Post-transcriptional Regulation of ß-Secretase (Bace1) and a-Secretase (Adam10)
(Project Heads
Haass, Christian
;
Lammich, Sven
;
Willem, Michael
)
Selective autophagy in proteostasis maintenance
(Project Head
Behrends, Ph.D., Christian
)
SFB 596: Molecular Mechanisms of Neurodegeneration
(Spokesperson
Haass, Christian
)
Major Research Instrumentation
Completed projects
Hochleistungsmassenspektrometer mit nano-UHPLC Chromatographie-System
Liquid handling platform
Research Training Groups
Completed projects
GRK 1373: Brain Signalling: From Neurons to Circuits
(Spokesperson
Konnerth, Arthur
)
Clusters of Excellence
Completed projects
EXC 1010: Munich Cluster for Systems Neurology (SyNergy)
(Spokesperson
Haass, Christian
)
Clusters of Excellence (ExStra)
Current projects
EXC 2145: Munich Cluster for Systems Neurology (SyNergy)
(Spokespersons
Haass, Christian
;
Misgeld, Thomas
)
