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Project Details
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Institution
Dana-Farber Cancer Institute
Address
450 Brookline Avenue
Boston MA 02215
USA
Boston MA 02215
Projects
Research Fellowships
Completed projects
A new molecular multimodal imaging strategy in brain tumor surgery: Nanoparticle-dependent raman spectroscopy and multispectral optoacoustic tomography for enhancing resection of malignant gliomas.
(Applicant
Neuschmelting, Volker
)
Effect of somatic STAG2 mutations on clonal hematopoiesis in GATA2 associated familial myelodysplastic syndromes
(Applicant
Schäfer, Eva Johanna
)
Einschleusung magnetischer Nanopartikel in Lymphozyten mittels CLIO-Tat: Optimierung der Methode und Anwendung in vivo
(Applicant
Kircher, Ph.D., Moritz
)
Evaluation of non-protein coding breast cancer risk regions discovered through genome wide association studies
(Applicant
Rath, Michelle
)
How does the interaction of protein phosphatase 2A and small t antigen lead to activation of the PI3K pathway and subsequent transformation of primary human cells? Determination of the level of interaction and elucidation of the mechanism
(Applicant
Utermark, Tamara
)
Identification and targeting of key oncogenic drivers in pediatric and adult H3K27M-gliomas at the single-cell level
(Applicant
Liu, Ilon
)
Identification of new targets to overcome resistance to hypomethylating agents and venetoclax in acute myeloid leukemia
(Applicant
Schneider, Ph.D., Constanze
)
Intraoperative imaging for detection and therapy of microscopic lesions of peritoneal disease in a murine ovarian cancer model with novel SERRS nanostars
(Applicant
Oseledchyk, Anton
)
Isolierung von Tumorstammzellen aus Kolonkarzinomen
(Applicant
Horst, David
)
Programmed death ligand 1 (PD-L1) cell-intrinsic signaling in pancreatic cancer – Influence on tumor metabolism, microenvironment and disease progression
(Applicant
Heckler, Max
)
Soziale Informationsverarbeitung als Mediationsmodell und ihr Einfluss auf depressives und aggressives Verhalten
(Applicant
Pössel, Patrick
)
The role of inflammatory mediators produced in Dnmt3a-driven clonal hematopoiesis and the effects on cardiovascular disease
(Applicant
Stomper, Julia
)
WBP Fellowship
Current projects
Augmenting the Anti-Tumor Immunity of CAR Armed Cytokine-Induced Memory-Like Natural Killer Cells by Novel CD73-directed Checkpoint Immunocytokines in AML
(Applicant
Sendker, Stephanie
)
Deciphering cellular interaction between malignant and normal brain cells in pediatric high-grade gliomas
(Applicant
Neyazi, Sina
)
Deciphering the role of disordered regulatory motifs in activator and inhibitor of the G2 to M transition cell-cycle checkpoint
(Applicant
Toerner, Ph.D., Ricarda
)
How chromosomes deal with trauma – do delayed replication and repressed transcription protect previously mis-segregated chromosomes against chromothripsis?
(Applicant
Reusswig, Karl-Uwe
)
Impact of physical activity and obesity on early pancreatic carcinogenesis
(Applicant
Roth, Laura
)
Investigation of a novel microdevice for drug evaluation and discovery in non-clear cell renal cell carcinoma
(Applicant
Steiner, Clara
)
The role of the immune infiltrate in transformation of follicular lymphoma to aggressive lymphoma
(Applicant
Beckmann, Laura
)
Completed projects
Epigenetic transcriptional control of intestinal epithelial regionality
(Applicant
Kraiczy, Ph.D., Judith
)
Identification and characterization of novel exercise-induced, muscle-secreted proteins and their role in health and disease
(Applicant
Mittenbühler, Melanie
)
Immune Checkpoint and Epigenetic Inhibition in Anaplastic Thyroid Cancers
(Applicant
Haase, Jacob
)
In vivo targeting of hematopoietic stem cells to treat sickle cell disease
(Applicant
Klatt, Denise
)
Research Grants
Current projects
Discovery of Chemical and Biological Tools for Reprogramming the Transcription Factor BCL6 Through Chemically Induced Proximity Modalities
(Applicants
Nowak, Ph.D., Radoslaw
;
Steinebach, Christian
)
Completed projects
Wirkkomponenten universaler Prävention von Depressionen bei Jugendlichen
(Applicant
Hautzinger, Martin
)
Clinical Research Units
Current projects
Building health intelligence with complex data on tumor cell states and therapy resistance
(Applicants
Horn, Susanne
;
Schadendorf, Dirk
)
Subinstitutions
Armstrong Lab
Boston Childrens's Cancer and Blood Disorders Center
Department of Cancer Biology
Department of Cancer Immunology and Virology
Department of Pediatric Oncology
The Letai Lab
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