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Universitätsklinikum Hamburg-Eppendorf
Zentrum für Innere Medizin
III. Medizinische Klinik und Poliklinik

Address Martinistraße 52
20251 Hamburg
Deutschland

GERiT This institution in GERiT

20251 Hamburg

Projects

Research Grants
- Current projects
- Completed projects
Research Fellowships
- Completed projects
Emmy Noether International Fellowships
- Completed projects
  - Mechanismen dynamischer Schlitzmembranfunktionen
    (Applicant Huber, Tobias B. )
Clinical Research Units
- Current projects
  - KFO 5010: CATCH ALL Towards a Cure for Adults and Children with Acute Lymphoblastic Leukemia (ALL)
    (Spokesperson Baldus, Claudia )
- Completed projects
  - Characterization of inflammatory cells and mediators in human glomerulonephritis
    (Applicant Stahl, Rolf A.K. )
  - Function of chemokine receptors in T cell-mediated glomerulonephritis
    (Applicant Panzer, Ulf )
  - KFO 228: Immunopathogenesis and Therapy of Glomerulonephritis
    (Spokesperson Stahl, Rolf A.K. )
  - KFO 296: Feto-maternal immune cross talk: Consequences for maternal and offspring's health
    (Spokesperson Arck, Petra Clara )
  - Metabolisches Lernen - Wird die Adaptation an wiederholte Hypoglykämien durch glutamaterge Mechanismen vermittelt?
    (Applicant Pais, Isabel )
  - Regulation of the Th17 response in glomerulonephritis
    (Applicant Steinmetz, Oliver Michael )
  - Role of NF-kB in glomerulonephritis
    (Applicant Thaiss, Friedrich )
  - Structural development of the Clinical Research Unit 228
    (Applicant Panzer, Ulf )
  - The Role of mTOR dependent and independent signalling pathways for renal tubular cystogenesis
    (Applicants Huber, Tobias B. ; Reichardt, Wilfried )
Heisenberg Fellowships
- Completed projects
  - Center for Glomerular Disease and Aging (CGDA)
    (Applicant Huber, Tobias B. )
Heisenberg Professorships
- Completed projects
  - Chronische Nierenerkrankungen und Altersforschung
    (Applicant Huber, Tobias B. )
Independent Junior Research Groups
- Current projects
  - Molecular Mechanisms of Membranous Nephropathy – New Avenues Towards an Individualized Therapy
    (Applicant Tomas, Nicola )
- Completed projects
  - Dynamische Podozytenfunktion zur Regulation des Nierenfilters
    (Applicant Huber, Tobias B. )
  - Innate lymphoid cells in renal inflammation
    (Applicant Turner, Jan-Eric )
Heisenberg Grants
- Current projects
  - Organ Immunology and Disease Modelling
    (Applicant Bunders, Ph.D., Madeleine )
  - Personalized treatment of immune-mediated glomerular diseases
    (Applicant Hoxha, Elion )
Priority Programmes
- Completed projects
  - Tissue-specific mechanisms of ILC2 adaptation and plasticity
    (Applicant Turner, Jan-Eric )
Collaborative Research Centres
- Current projects
  - Decoding of crescent fate in an integrative and translational approach
    (Project Heads Grahammer, Florian ; Puelles, Ph.D., Victor G. ; Zimmermann, Marina )
  - Elucidating principles of kidney and organ involvement in emerging viral infections
    (Project Head Huber, Tobias B. )
  - Function and regulation of systemic and local complement C3 in immune-mediated kidney diseases
    (Project Heads Freiwald, Tilo ; Wiech, Thorsten )
  - Function of effector Treg subsets in glomerulonephritis
    (Project Head Steinmetz, Oliver Michael )
  - Hamburg Glomerulonephritis Registry
    (Project Heads Hoxha, Elion ; Huber, Tobias B. ; Lindenmeyer, Maja ; Wiech, Thorsten )
  - High-dimensional single cell profiling in renal autoimmune diseases
    (Project Heads Bonn, Stefan ; Krebs, Christian ; Panzer, Ulf )
  - Identifying pathways and factors causing primary focal segmental glomerulosclerosis
    (Project Heads Huber, Tobias B. ; Mühlig, Anne Katrin )
  - Impact of purinergic signaling on epithelial cell-adipocyte crosstalk in intestinal inflammation and fibrosis in Crohn’s Disease
    (Project Heads Bunders, Ph.D., Madeleine ; Worthmann, Anna )
  - Innate and innate-like lymphocytes in immune-mediated glomerular diseases
    (Project Heads Bunders, Ph.D., Madeleine ; Turner, Jan-Eric )
  - Management and Coordination of the CRC
    (Project Head Huber, Tobias B. )
  - Mechanisms and function of T cell derived cytokines in crescentic glomerulonephritis
    (Project Head Panzer, Ulf )
  - Mechanisms of Immune-Mediated Tissue Injury
    (Project Heads Harendza, Sigrid ; Panzer, Ulf )
  - Membranous Nephropathy: Pathogenetic Mechanisms and Clinical Implications
    (Project Heads Hoxha, Elion ; Reinhard, Linda )
  - Nanobody-based treatment strategies in glomerulonephritis
    (Project Heads Tomas, Nicola ; Wanner, Nicola )
  - Proteolytic control of immune-mediated kidney diseases
    (Project Head Rinschen, Markus )
  - SFB 1192: Immune-Mediated Glomerular Diseases - Basic Concepts and Clinical Implications -
    (Spokespersons Huber, Tobias B. ; Panzer, Ulf )
  - Structural and functional characterization of podocyte antigens in autoantibody-mediated glomerulonephritis
    (Project Heads Hengel, Felicitas E. ; Huber, Tobias B. ; Wilmanns, Ph.D., Matthias )
  - Targeting Th17 cell adaptation in renal autoimmune diseases
    (Project Heads Huber, Samuel ; Krebs, Christian )
  - The (immuno)proteasome as a modifier of podocyte membrane dynamics in membranous nephrophathy
    (Project Heads Köhler, Sybille ; Meyer-Schwesinger, Catherine )
- Completed projects
  - Development of the Glomerular Filter
    (Project Heads Huber, Tobias B. ; Kramer-Zucker, Albrecht )
  - Epigenetic programming of kidney development
    (Project Head Huber, Tobias B. )
  - High-resolution proteomics and functional analyses of the podocyte slit diaphragm and its disease-induced dynamics
    (Project Heads Fakler, Bernd ; Grahammer, Florian )
  - High-resolution structural and global signaling network identification of the NEPH-NEPHRIN protein complex
    (Project Head Huber, Tobias B. )
  - The innate immune response in hypertensive glomerular injury
    (Project Heads Ehmke, Heimo ; Wenzel, Ulrich )
Research Units
- Current projects
  - FOR 2743: Mechanical Stress Protection
    (Spokesperson Höhfeld, Jörg )
  - FOR 5211: Persistent Somatic Symptoms Across Diseases: From Risk Factors to Modification
    (Spokesperson Löwe, Bernd )
  - Mechanical stress protection at the kidney filtration barrier
    (Applicants Benzing, Thomas ; Rinschen, Markus )
  - Predictors of Somatic Symptom Persistence in Patients With Chronic Kidney Disease (RU SOMACROSS)
    (Applicants Huber, Tobias B. ; Shedden Mora, Ph.D., Meike )
Major Research Instrumentation
- Completed projects
  - 5-Laser Flow Cytometer
WBP Fellowship
- Current projects
  - The role of IFITM1 and IFITM3 in kidney disease
    (Applicant Dumoulin, Bernhard )
Graduate Schools
- Completed projects
  - GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED)
    (Spokesperson Borner, Christoph )

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