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Klinikum der Technischen Universität München (TUM Klinikum)
Klinik und Poliklinik für Innere Medizin III: Hämatologie und Onkologie

Address Ismaninger Straße 22
81675 München
Deutschland

GERiT This institution in GERiT

81675 München

Projects

Research Grants
- Current projects
- Completed projects
Independent Junior Research Groups
- Current projects
  - Engineering resilient CAR-T against resistant cancer cells
    (Applicant Schmidts, Andrea )
- Completed projects
  - The analysis of mouse models in order to define the roles of IKK/NF-KappaB and JNK signaling in lymphocyte physiology and pathology
    (Applicant Schmidt-Supprian, Marc )
  - Ubiquitin-vermittelte Proteolyse als Steuermechanismus der DNA-Replikation und DNA-Schaden Antwort - Bedeutung für die Tumorentstehung
    (Applicant Bassermann, Florian )
Research Units
- Current projects
  - FOR 2033: The Hematopoietic Niches
    (Spokesperson Oostendorp, Robert A.J. )
  - FOR 5560: Crosstalk between B cell metabolism and signaling
    (Spokesperson Jellusova, Julia )
  - Targetable metabolic dependencies in CLL
    (Applicants Buchner, Maike ; Eichner, Ph.D., Ruth )
- Completed projects
  - Coordination Funds
    (Applicant Oostendorp, Robert A.J. )
  - Dissecting Lymphoma Niche Interactions
    (Applicant Schmidt-Supprian, Marc )
  - Individuelle in vivo-Dosimetrie bei der Therapie mit offenen radioaktiven Nukliden
    (Applicant Scheidhauer, Klemens )
  - Role of Secreted frizzled-related Protein 1 (Sfrp 1) in the function of the hematopoietic niche
    (Applicant Oostendorp, Robert A.J. )
WBP Return Grant
- Completed projects
  - Rückkehrstipendium
    (Applicant Haertle, Larissa )
Collaborative Research Centres
- Current projects
  - Differentiation pathways of semi-invariant innate-like T-cells
    (Project Head Schmidt-Supprian, Marc )
  - The role of the NPM-ALK / PD-1 axis for immune response to T cell lymphoma
    (Project Head Illert, Lena )
- Completed projects
Research Fellowships
- Completed projects
Heisenberg Fellowships
- Completed projects
  - The Role of Roquin in Immune Cell Physiology and Pathology
    (Applicant Schmidt-Supprian, Marc )
WBP Fellowship
- Current projects
  - The role of the reductive stress response as a vulnerability in hematologic malignancies
    (Applicant Heider, Michael )
- Completed projects
  - Identification of new cancer specific genetic and epigenetic biomarkers for cancer evolution and Minimal Residual Disease (MRD) in peripheral blood samples
    (Applicant Haertle, Larissa )
  - Metabolic reprogramming of Trimeric APRIL-CAR-engineered Natural Killer (NK) cells to enhance tumor-cell recognition, in vivo persistence and anti-tumor potency in Multiple myeloma
    (Applicant Biederstädt, Alexander )
CRC/Transregios
- Current projects
  - Central Tasks
    (Project Head Bassermann, Florian )
  - Cross-species screens and investigation of UPS vulnerabilities in high grade lymphoma
    (Project Head Schmidt-Supprian, Marc )
  - Deciphering vulnerabilities in the USP1/Fanconi anemia axis as anticancer target in AML
    (Project Heads Buettner, Ph.D., Florian ; Illert, Lena )
  - Investigating Treg cell plasticity in mice and man
    (Project Heads Schmidt-Supprian, Marc ; Schumann, Kathrin )
  - Role of FBXO41 in maintaining the undifferentiated state in acute myeloid leukemia
    (Project Head Bassermann, Florian )
  - SLC-regulating E3 ligases as therapeutic targets in AML
    (Project Head Eichner, Ph.D., Ruth )
  - Targeting neoantigens in multiple myeloma by TCR-transgenic T cells
    (Project Head Krackhardt, Angela )
  - Targeting OTUD6B in multiple myeloma
    (Project Heads Bassermann, Florian ; Hadian, Ph.D., Kamyar )
  - TRR 387: Functionalizing the Ubiquitin System against Cancer - UbiQancer
    (Spokesperson Bassermann, Florian )
- Completed projects
Research Training Groups
- Current projects
  - GRK 2668: Immune Master Switches in Allergies and Autoimmune Diseases
    (Spokesperson Biedermann, Tilo )

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