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Project Details

Institution

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Charité Universitätsklinikum
Campus Virchow-Klinikum
Institut für Medizinische Genetik und Humangenetik

Address Augustenburger Platz 1
13353 Berlin
Deutschland

GERiT This institution in GERiT

13353 Berlin

Projects

Clinical Research Units
- Completed projects
  - Untersuchungen zur molekularen Biologie der Frakturheilung am Schafsmodell
    (Applicant Mundlos, Stefan )
Research Grants
- Current projects
- Completed projects
Priority Programmes
- Current projects
  - Position effects in the 3D genome as the cause of neurodevelopmental disorders
    (Applicant Spielmann, Malte )
- Completed projects
Research Units
- Completed projects
  - Physiological relevance of genetic risk variants in reduced penetrance
    (Applicants Kaiser, Frank ; Spielmann, Malte ; Westenberger, Ana )
  - Sex differences in the cardiac proteome in myocardial hypertrophy
    (Applicant Klose, Joachim )
  - The effects of non-coding duplications on gene regulation and disease pathology
    (Applicant Mundlos, Stefan )
  - The role of cellular senescence in bone regeneration
    (Applicants Fischer-Zirnsak, Björn ; Geißler, Sven )
Heisenberg Grants
- Completed projects
  - Human Molecular Genomics
    (Applicant Spielmann, Malte )
Collaborative Research Centres
- Current projects
  - The mechano‐genomic code: pioneer factors as decision makers
    (Project Heads Knaus, Petra ; Mundlos, Stefan )
  - The single cell transcriptional and chromatin landscape of sex differentiation and the role of the androgen pathway in extra-genital somatic tissues
    (Project Heads Holterhus, Paul-Martin ; Spielmann, Malte )
- Completed projects
  - Analysis of the Receptor Tyrosine Kinase Ror2: A Central Modulator in the Brachydactyly Disease Family
    (Project Heads Mundlos, Stefan ; Stricker, Sigmar )
  - Central Facility for Animal Model Generation and Characterization
    (Project Heads Mundlos, Stefan ; Walther, Diego J. )
  - Central tasks of the Collaborative Research Centre
    (Project Heads Mundlos, Stefan ; Sperling, Karl )
  - Clinical and Genetic Assessment Unit
    (Project Heads Mundlos, Stefan ; Schülke-Gerstenfeld, Markus )
  - Core Facility Proteomics, service and collaboration within the SFB
    (Project Heads Klose, Joachim ; Mao, Lei ; Wanker, Erich E. )
  - DNA Microarry Center
    (Project Heads Nuber, Ulrike ; Sperling, Karl )
  - Improving bone regeneration by modification of BMP-inhibition
    (Project Heads Mundlos, Stefan ; Seemann, Petra )
  - Molecular Pathology and Embryology of HOXD and BMP Related Limb Malformations
    (Project Heads Mundlos, Stefan ; Seemann, Petra )
  - Nijmegen Breakage Syndrome (NBS): A link between radiosensitivity, chromosomal instability and immunodeficiency
    (Project Heads Digweed, Martin J. ; Sperling, Karl )
  - SFB 577: Molecular Basis of Clinical Variability in Mendelian Disorders
    (Spokesperson Mundlos, Stefan )
  - Sonic hedgehog regulation during development and in disorders of the nervous system
    (Project Heads Mundlos, Stefan ; Schwabe, Georg C. )
  - The effect of mutations on proteome networking
    (Project Heads Klose, Joachim ; Mao, Lei )
  - The molecular biology of fracture healing
    (Project Heads Mundlos, Stefan ; Robinson, Peter Nicholas )
Major Research Instrumentation
- Completed projects
  - Sequenziergerät
Research Fellowships
- Completed projects
  - Non-coding genetic variants in human disease
    (Applicant Spielmann, Malte )
Reinhart Koselleck Projects
- Completed projects
  - 3D Genome Architecture in Congenital Disease
    (Applicant Mundlos, Stefan )
CRC/Transregios
- Completed projects
  - Control of cellular TH metabolism in human and mouse NASH
    (Project Heads Kirchner, Henriette ; Mittag, Jens ; Spielmann, Malte )
Research Training Groups
- Completed projects
  - GRK 754: Myocardial Gene Expression und Function - Myocardial Hypertrophy
    (Spokesperson Regitz-Zagrosek, Vera )
International Research Training Groups
- Completed projects
  - GRK 2403: Dissecting and Reengineering the Regulatory Genome
    (Spokesperson Ohler, Uwe )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2167: Precision Medicine in Chronic Inflammation (PMI)
    (Spokesperson Schreiber, Stefan )
Graduate Schools
- Completed projects
  - GSC 203: Berlin-Brandenburg School for Regenerative Therapies (BSRT)
    (Spokesperson Duda, Georg )

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